Researchers have developed a compact, affordable intraoral device that integrates diagnostic imaging and photodynamic therapy to detect and treat early-stage oral cancer. Designed for use in low-resource settings, the handheld tool uses fluorescence imaging to identify lesions and delivers targeted light therapy to destroy cancerous tissue. Preclinical studies in tissue models and mice demonstrated effective tumor reduction and capability for treatment monitoring. This innovation could significantly improve access to timely oral cancer care in regions with limited medical infrastructure.

A new international research project featuring faculty at Binghamton University, State University of New York reveals that people in the Middle Ages weren’t cooped up in castles, wallowing in superstition. They were developing health practices based on the best knowledge they had at the time – some of which mirror modern wellness trends.

New York, NY, July 15, 2025—Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring disease. Their findings, demonstrated across cell cultures, preclinical models, and samples of human lung tissue, show that blocking Epac1 can slow the progression of the disease.

Published in the July 7 online issue of European Respiratory Journal [https://doi.org/10.1183/13993003.02250-2024], the work could pave the way for a new class of treatments to help patients with this currently incurable condition. Published in the July 7 online issue of European Respiratory Journal [https://doi.org/10.1183/13993003.02250-2024], the work could pave the way for a new class of treatments to help patients with this currently incurable condition.