Young people who are diagnosed with conduct disorder show significant differences in their brain structure depending on whether or not they have also suffered childhood abuse, according to new research led by the University of Bath in the UK. This finding suggests the combined effects of childhood maltreatment and conduct disorder impact the architecture of the brain.

Immune environments in most tongue cancer tumors help identify cases for effective treatment, report researchers from Institute of Science Tokyo. By profiling immune cell presence and activity in tumor samples from 87 patients, they identified five immunotypes, with most patients categorized in these immunotypes featuring low immune engagement. These findings explain why immune checkpoint inhibitors prove inefficacious in tongue cancer and suggest that immune-based classification could better guide personalized treatment strategies.

A study from Fujita Health University reveals that meal type, rather than meal sequence, significantly impacts how long people eat, how much they chew, and how fast they chew. Bento meals—typically eaten with chopsticks—led to longer mealtimes and more chewing than fast food like pizza. This is the first study to isolate meal structure as a key factor in eating speed, offering simple, practical strategies to combat obesity and promote mindful eating.

In a step towards engineering artificial cell membranes, researchers at Institute of Science Tokyo (Science Tokyo) used quartz crystal microbalance with energy dissipation monitoring (QCM-D) to study how DNA nanopores interact with lipid bilayers. Unlike conventional optical methods, QCM-D tracks changes in mass and viscosity in real time, offering unique mechanical insights into DNA–lipid interactions. This approach paves the way for designing DNA-based membrane technologies that modify the functionality of cell lipid membranes.  

In response to the COVID-19 outbreak, precautionary measures were swiftly adopted. While the early pandemic effects were studied extensively, little is known about long-term impacts on vulnerable groups like the elderly. Researchers in Japan analyzed healthcare use and socioeconomic disparities among older adults during the prolonged pandemic. Their findings reveal both resilience and inequality—offering crucial insights into how healthcare systems can adapt to maintain access for aging populations during extended public health emergencies.

Miniature organs on a chip could allow us to do scientific studies with great precision, without having to resort to animal testing. The main problem, however, is that artificial tissue needs blood vessels, and they are very hard to create. Now, a new technology has been developed to create reproducible blood vessels using high-precision laser pulses. Tissue has been created that acts like natural tissue.