University of Virginia School of Medicine and Naval Medical Research Command (NMRC) researchers will use a federal Department of Defense grant to better identify, prevent and treat brain injuries for military personnel caused by repeated blast exposures.

A team of researchers at IOCB Prague headed by Dr. Tomáš Slanina has developed a new method for labeling molecules with fluorescent dyes that surpasses existing approaches in both precision and stability. The new fluorescent label remains covalently bonded to its target molecule and does not fall apart even under demanding conditions inside living cells. This allows scientists to track labeled molecules over long periods with high reliability – an advantage for research in biology, chemistry, and medicine. The study was published in Angewandte Chemie International Edition.

Current antibody-based treatments for Alzheimer’s disease remain costly and carry significant side effects, highlighting the need for safer alternatives. In a new study, researchers from Kindai University report that oral administration of arginine suppresses amyloid-β aggregation and related neurotoxicity in fruit fly and mouse models of Alzheimer’s disease. Their findings demonstrate arginine’s potential as a safe, inexpensive, and readily available repositioned drug candidate for preventing or mitigating Alzheimer’s pathology.