UOsaka and MIT scientists revealed that the motor proteins KIF18A and CENP-E work together to align chromosomes during mitosis. Cancer cells with reduced CENP-E levels are especially sensitive to KIF18A inhibition, and dual inhibition of both proteins leads to efficient cell death. The discovery offers new insights into chromosome mechanics and a potential strategy for targeted cancer therapy.

Sanjay Rajagopalan, MD, MBA, Chief of Cardiovascular Medicine at University Hospitals Harrington Heart & Vascular Institute and Director of the Case Cardiovascular Research Institute at Case Western Reserve University School of Medicine, has earned the 2025 American Heart Association Distinguished Scientist Award. This honor recognizes individuals whose work has significantly advanced the understanding of cardiovascular disease and stroke.

Researchers at The University of Texas at Arlington are pursuing a potential breakthrough that could help soldiers recover from devastating blast injuries. Zui Pan, professor of graduate nursing at UT Arlington, is leading the 20-month study exploring how zinc might protect and regenerate muscle tissue damaged by trauma.

A team investigating the pediatric inflammatory disease juvenile dermatomyositis (JDM) has received a € 350,000 grant from the Prinses Beatrix Spierfonds (Dutch Neuromuscular Foundation) for the development of a model that more accurately can predict disease progress. The JDM research team - consisting of Prof. Annet van Royen-Kerkhof, MD PhD, Dr. Marc Jansen, MD PhD, Prof. Femke van Wijk, PhD, and PhD candidate Jan Willem Marsden, MD - concerns a long-term collaboration between the Wilhelmina Children's Hospital (WKZ) and the Center for Translational Immunology (CTI) at UMC Utrecht.