The Keck School of Medicine of USC and Keck Medicine of USC have launched collaborations with Tempus AI, Inc., a technology company at the forefront of applying AI to precision medicine, to integrate clinical care, clinical trials and research through a unified framework. The new framework intends to create an ongoing cycle of learning between patient care and research, with a primary goal of improving outcomes for the more than 1.5 million annual patient visits to Keck Medicine of USC hospitals and clinics. It is designed to promote more personalized and precise care to patients across the Keck Medicine of USC health system with tailored recommendations informed by large-scale clinical data. At the same time, it seeks to use clinical data to inform and accelerate research to develop innovative therapies and algorithms that may translate for public benefit. At the heart of the USC -Tempus collaboration is the pioneering research and patient care delivered by the USC Norris Comprehensive Cancer Center. The strategic undertaking is anchored by four key pillars. These include clinical testing, which can enable detailed molecular and genetic profiling at the patient level; clinical trials matching, which automatically matches eligible patients with novel targeted therapies; clinical care gap pathways, which uses AI-driven insights to promote evidence-based patient care; and research collaboration and co-development, aimed at moving academic discoveries into real-world diagnostics and treatments. Together, these elements have the potential to create an integrated ecosystem that connects patient care and research. This collaboration will start with a focus on precision oncology, with the intension of creating a proven model for integrating care and research, that can then be extended over time to other specialties, including cardiology, neurology and radiology.

The security of every nation faces an increasingly severe and frequent threat: disruptions to nature. In this Q&A, Bradley J. Cardinale, Penn State professor of ecosystem science and management, discussed his recent study examining how disrupted ecosystems can lead to increased risk for food security, water availability, health and well-being, as well as crime. 

Researchers at LMU have developed a human cell model that replicates key mechanisms of neurodegenerative diseases – with potential for novel therapies.

People with the most severe strokes have five times higher odds of developing dementia and show cognitive decline equivalent to being more than two years older at baseline compared with people who do not have a stroke, according to a national study led by Michigan Medicine researchers.

New research has been published ahead-of-print by The Journal of Nuclear Medicine (JNM). JNM is published by the Society of Nuclear Medicine and Molecular Imaging, an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes.