Introducing Genos, an open genomic foundation model for high-quality human genomes across global populations, built to advance understanding of the genome and its diversity. Genos achieves single-nucleotide precision over a context of 1 million bases and uses a Mixture of Experts (MoE) architecture that is practical to deploy and economical to run. We provide two variants, 10B and 1.2B, so teams can match compute and latency needs. Trained on 636 high-quality assemblies representing diverse ancestries, with ~1.6T training tokens for the 1.2B model and ~2.2T for the 10B model, Genos learns the genome itself and generalizes to population-scale analyses. With efficient routing and scalable inference, Genos connects sequence to function and powers tools for discovery and diagnostics, and a complementary 4B multimodal language model pairs genomic signals with text to enable omics-aware reasoning in those tools. Explore code, weights, and docs on GitHub, Hugging Face, ModelScope, and zero2x.

Feeling sluggish?

A new study from The University of Texas at Arlington finds the fix may be as simple as swapping 30 minutes of sitting for light activity.

A Harvard study shows that commercially available sensors worn on a runner's body can provide useful data on what researchers call ground-reaction forces. These insights could open avenues to devices and products that deliver this data in real time to help runners avoid injury and improve their form.

With the help of a five-year, nearly $1.98 million Maximizing Investigators’ Research Award (MIRA) (R35) from the National Institute of General Medical Sciences of the National Institutes of Health, researchers at Wayne State University aim to make strides in understanding how proteins move and interact in living cells through the development of next-generation computational modeling tools.

The Association for Molecular Pathology has awarded Michael Laposata, M.D., Ph.D., its Champion for Innovation Award. Laposata was recognized for his contributions to the clinical laboratory field and for his role as a joint plaintiff in AMP’s successful lawsuit challenging the U.S. Food and Drug Administration’s rule on laboratory-developed test procedure regulation. The award will be presented in November during the AMP 2025 Annual Meeting & Expo in Boston.