In this cohort study, receipt of the 2024-2025 COVID-19 vaccine was associated with reduced risk of COVID-19–associated major adverse cardiovascular event (MACE), with reductions most prominent in those 75 years or older and those with comorbidities. While the reduction in COVID-19–associated MACE was modest, the substantially larger reduction in all-cause MACE suggests that the vaccine’s protective association extends to the hidden burden of undetected SARS-CoV-2 and its sequelae. 

In this test-negative case-control study, 2024-2025 COVID-19 vaccination was associated with reduced likelihood of medically attended COVID-19–associated outcomes among immunocompetent and immunocompromised adults, highlighting the importance of adults receiving recommended COVID-19 vaccinations. 

In this repeated cross-sectional analysis of NHANES 1999 to 2023, supplement use among U.S. adults increased over time, with diversification beyond multivitamin-multiminerals toward products marketed for immune, anti-inflammatory, gut, skin, or joint health. A substantial increase was observed in older adults. Ongoing monitoring of supplement use trends is needed to understand evolving public health implications.

Scientists have revealed striking inequalities and changing trends in medicines dispensing for more than 52 million people living in England during and after the COVID-19 pandemic.

“Alzheimer’s-Related Psychosis: Interdisciplinary Perspectives for Understanding and Responding to Delusions and Hallucinations” — the latest report in The Gerontological Society of America’s Insights & Implications in Gerontology series — underscores the clinical, emotional, and societal impact of psychosis in individuals living with Alzheimer’s disease and stresses the need for comprehensive, person-centered approaches to care.

College students have rapidly adopted generative AI, but critical questions remain about its use for mental health support. In a study co-led by investigators at Mass General Brigham, 18% of surveyed college students reported using artificial intelligence (AI) for mental health. Students with more severe mental health symptoms were more likely to do so. The findings are published in the Journal of Affective Disorders.