Elucidating the functional dynamics of DNASE1L2 intron retention in tuberculosis progression
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Jun-2026 14:16 ET (23-Jun-2026 18:16 GMT/UTC)
Dentists are exposed to intense lighting for long hours, but its long-term impact on eye health is often overlooked. This study evaluates whether chronic exposure to dental lighting, especially blue and white LEDs, can damage the retina and disrupt its normal function. By combining human data with advanced imaging and animal models, the research uncovers hidden occupational risks and highlights the need for safer lighting practices to help protect dentists’ vision.
A doctoral thesis by Amal D. Premarathna shows that polysaccharides derived from algae have strong wound-healing, anti-inflammatory, and skin-protective properties. These findings highlight algae as a promising, sustainable alternative to synthetic treatments for chronic wounds and related health applications.
Acute myeloid leukemia (AML) remains one of the most difficult blood cancers to treat. Although drug combinations are often more effective than single agents, their true mechanisms of action have been poorly understood. A new study introduces CoPISA – the Combinatorial Proteome Integral Solubility/Stability Alteration analysis, a powerful high‑throughput proteomics workflow that uncovers how drug combinations reshape the soluble proteome in ways that single drugs cannot.
Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified and described a previously unknown recessive neurodevelopmental disorder (NDD) that appears to be the most prevalent ever discovered. The condition is caused by changes in a small noncoding gene called RNU2-2. It is estimated to affect thousands of individuals in the United States and account for about 10 percent of all recessive NDD cases with a known genetic cause. The work was done in collaboration with U.S. collaborators in the Undiagnosed Diseases Network led by colleagues at Stanford University and international collaborators in the United Kingdom, the Netherlands, Belgium, and Italy. The findings, published in the March 30 issue of Nature Genetics [https://doi.org/10.1038/s41588-026-02539-5], provide long-awaited answers for many families and may inform future drug development.
Large-scale genomic analysis of Latin American cohort supports universal genetic architecture of autism and advances equity in precision medicine