Scientists at The Jackson Laboratory have finally pinpointed why patients with mitochodrial disease get so sick. 

In the future, autonomous delivery drones could independently assess whether their remaining battery charge is sufficient for upcoming deliveries. A team of researchers from Technical University of Darmstadt and the University of Sheffield, in collaboration with the French National Institute for Research in Digital Science and Technology (INRIA) and industry partner Ingeniarius Ltd, has developed a new method for energy-aware deployment planning. The approach enables each drone to learn what orders it is capable of fulfilling even when not knowing its own battery health . It is shown to reduce delivery times and increase the number of processed orders compared to conventional approaches.

Structural inequalities, including wealth inequality and social segregation, not only make certain groups more vulnerable during public health crises but also accelerate the spread of infectious diseases through society, according to a team of international researchers. 

This study introduces ​​gPRINT​​ (generalized approach for cell subtype Identification with single cell's voicePRINT), a novel algorithm designed to unify the annotation of disease-specific cell subtypes (DSCSs) across heterogeneous single-cell datasets(scRNA-seq). By integrating gene expression levels and chromosomal positional information into unique "gene prints," gPRINT overcomes the limitations of conventional annotation methods, enabling high-precision identification of cell subtypes in complex diseases such as fibrosis and tendinopathy.Validated across multiple platforms and tissues, gPRINT achieved an external validation accuracy of ​​98.37%​​, surpassing existing tools and offering transformative potential for precision medicine.