The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: May 2, 2025
Peer-Reviewed Publication
Updates every hour. Last Updated: 27-Jul-2025 16:10 ET (27-Jul-2025 20:10 GMT/UTC)
Many mitochondrial diseases have been difficult to study and treat due to the inherent challenges in accessing mitochondrial DNA (mtDNA). Now, researchers from Japan have optimized mitochondrial-targeted compounds that can selectively modify the ratio of normal versus mutant mtDNA in patient-derived stem cells. This technology enables the creation of research models with varying mutation loads and demonstrates potential as a therapeutic strategy for reducing mutant mtDNA in patients, offering hope for mitochondrial disease treatment.
New research from Bayes Business School and biopharmaceuticals company Merck KGaA suggests member states from the European Union (EU) must work more closely together, provide better incentives for the development of new medicines and approve access to medicines quicker than other international regulators, if it is to attract greater investment from pharmaceutical companies.
Regular chats with friends, time spent in nature and mentally engaging activities are strongly linked to better mental health, according to new Curtin University research that highlights the power of simple, everyday behaviours to improve well-being.