For expectant mothers struggling with opioid use disorder, the stigma surrounding addiction can make it difficult to seek help.

Drew Herbert, a doctoral student at the University of Missouri Sinclair School of Nursing and a full-time nurse who has experience treating people with the disorder, has seen this firsthand.

Pennington Biomedical Research Center is pleased to announce the arrival of Dr. Adithya Hari, MD, as Assistant Professor and Physician/Nuclear Oncologist in the Division of Clinical Science, effective April 21. Dr. Hari’s recruitment represents a strategic expansion of Pennington Biomedical’s research capacity in cancer metabolism and nuclear medicine and was a collaborative effort involving Pennington Biomedical partners Mary Bird Perkins Cancer Center, Louisiana Cancer Research Center, and LSU Health New Orleans.

Ferroptosis, a form of programmed cell death mediated by iron, has been a focus for its potential in cancer therapies. Now, researchers have discovered that lysosomal lipid peroxidation plays a critical role in the execution of ferroptosis. They also showed that this leads to iron leakage from the lysosome, further promoting ferroptosis. Additionally, administration of chloroquine—a drug that promotes lysosomal membrane damage—facilitates ferroptosis in cancer cells that are less sensitive to the process.