A genomic analysis traces Indian ancestry back to a migration out of Africa around 50,000 years ago, after which humans interbred with Neanderthals and Denisovans and spread throughout Eurasia. About 10,000 years ago, farmers from Iran and nomadic herders from the Central Asian steppe mixed with the local hunter-gatherers. Then, 5,000 years ago, endogamy led to bottlenecks. This complex evolutionary history has shaped the genetic variation and health and disease in India.

Academic medical centers could transform patient care by adopting principles from learning health systems principles, according to researchers from Weill Cornell Medicine and the University of California, San Diego.

Veronique Dartois, Ph.D., a member of the Hackensack Meridian Center for Discovery and Innovation (CDI), authored the publication entitled, “Strategies for Shortening Tuberculosis Treatment”–with funding from the Bill and Melinda Gates Foundation–which shares a vision to personalize TB treatment for better patient care and more expedient curative outcomes.

In experiments with healthy volunteers undergoing functional MRI imaging, scientists have found increased activity in two areas of the brain that work together to react to, and possibly regulate, the brain when it’s “feeling” tired and either quits or continues exerting mental effort.