Duke-NUS scientists link waning Japanese encephalitis immunity to higher dengue severity
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Dec-2025 04:11 ET (30-Dec-2025 09:11 GMT/UTC)
Japanese encephalitis virus (JEV) vaccination both prevents JEV and lowers dengue severity.
Recently, a review titled "Circulating tumor cell-derived organoids: current progress, applications, and future" was published in MedComm - Future Medicine. The article systematically summarises the research progress, application scenarios, and future challenges of organoids derived from circulating tumor cells (CTCs). This study comprehensively reviews the biological characteristics of CTCs, strategies for their isolation and enrichment, optimisation techniques for in vitro culture systems, and their significance in basic research, translational medicine, and clinical applications.
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease.
Refractory wounds cause significant harm to the health of patients and the most common treatments in clinical practice are surgical debridement and wound dressings. However, certain challenges, including surgical difficulty, lengthy recovery times, and a high recurrence rate persist. Conductive hydrogel dressings with combined monitoring and therapeutic properties have strong advantages in promoting wound healing due to the stimulation of endogenous current on wounds and are the focus of recent advancements. Therefore, this review introduces the mechanism of conductive hydrogel used for wound monitoring and healing, the materials selection of conductive hydrogel dressings used for wound monitoring, focuses on the conductive hydrogel sensor to monitor the output categories of wound status signals, proving invaluable for non-invasive, real-time evaluation of wound condition to encourage wound healing. Notably, the research of artificial intelligence (AI) model based on sensor derived data to predict the wound healing state, AI makes use of this abundant data set to forecast and optimize the trajectory of tissue regeneration and assess the stage of wound healing. Finally, refractory wounds including pressure ulcers, diabetes ulcers and articular wounds, and the corresponding wound monitoring and healing process are discussed in detail. This manuscript supports the growth of clinically linked disciplines and offers motivation to researchers working in the multidisciplinary field of conductive hydrogel dressings.
Children in the North of England are waiting up to three years longer than those in the south for an autism diagnosis, new data analysis shows. The data, released by NHS England, reveals that children in Mid and South Essex are waiting on average 54 days for an assessment – falling within National Institute for Health and Care Excellence (NICE) guidelines of 13 weeks. However, in South Yorkshire, children wait on average 1,063 days – almost three years longer. It is the latest report to be released by the Child of the North initiative.