Carotid endarterectomy (CEA) is a surgical procedure to remove plaque buildup in the carotid artery, which supplies blood to the brain. Although its efficacy is known, the effect of CEA on the blood-brain barrier (BBB) properties has not been examined. Now, Chinese scientists have examined CEA-induced changes in the hemodynamic and BBB properties in patients with severe carotid artery stenosis using computed tomography perfusion scanning, demonstrating improved blood flow and enhanced BBB permeability reversal.

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan. Hypoxic conditions resulted in reduced alveolar bone levels after OTM and lower expression of runt-related transcription factor 2 and vascular endothelial growth factor. These findings, observed in a rat model, provide critical insights into the bone remodeling process in OTM under hypoxia.