Signal boost uncovers hundreds of hidden binding partners for blood protein receptor
Peer-Reviewed Publication
Updates every hour. Last Updated: 10-Jan-2026 05:11 ET (10-Jan-2026 10:11 GMT/UTC)
The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass. Finding a protein that isn’t in this top 10 is a bit like looking for Waldo if only one rendition of the character remained in a collection of every “Where’s Waldo” comic ever produced.
Scientists at Sanford Burnham Prebys and colleagues at Scripps Research Institute published findings July 7, 2025, in Nature Communications demonstrating a strategy for identifying less-abundant proteins that bind with a specific type of receptor termed an endocytic lectin, and namely the mannose receptor Mrc1. This approach enabled the research team to uncover hundreds of binding partners that together predicted Mrc1’s roles in our health.Cannabis use disorder is associated with a significantly higher risk of oral cancer, says new research from UC San Diego School of Medicine.
Teens who regularly use e-cigarettes are equally as likely as their peers from the 1970s to take up cigarette smoking, despite a substantial reduction in the prevalence of teenage cigarette use over the last 50 years, according to a study co-led by the University of Michigan.
A new study uses data from NASA’s PACE satellite to demonstrate a novel method for assessing global plant health. Led by UMBC’s Karl F. Huemmrich, the research leverages PACE’s Ocean Color Instrument to monitor plant responses, as indicated by reflectance from their leaves, to environmental changes like water availability and temperature. Validated against U.S. ground measurements, the technique accurately tracks plant productivity across diverse ecosystems without relying on weather data. The findings will enhance carbon sequestration tracking and early stress detection, offering a cost-effective way to monitor global ecosystems and support conservation and agriculture.
The research findings, published July 29 in the American Journal of Preventive Medicine, support promoting brisk walking as a strategy for improving health outcomes in all communities.