Studying chemical exposure and brain cancer risk in firefighters
Peer-Reviewed Publication
Updates every hour. Last Updated: 10-Sep-2025 14:11 ET (10-Sep-2025 18:11 GMT/UTC)
A new study uncovered an association between exposure to chemicals commonly used in firefighting and glioma risk, reinforcing earlier research that has suggested a link between firefighting and the development of cancers.
The small study led by Dr. Elizabeth B. Claus, a professor at the Yale School of Public Health, member of Yale Cancer Center, and founder of the International Low Grade Glioma Registry, showed that the glioma tumors of some firefighters had a distinctive genetic pattern or “mutational signature.” Those specific signatures were previously shown to be caused by exposure to chemicals called haloalkanes, which are associated with flame retardants, fire extinguishants, and propellants. The study results were published March 10 in Cancer, a peer-reviewed journal of the American Cancer Society.
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