About The Study: In this study, receipt of 2025-2026 COVID-19 vaccination was associated with additional protection beyond existing immunity in adults against medically attended COVID-19, including emergency department/urgent care encounters and hospitalizations, compared with no receipt of a 2025-2026 vaccine dose. These findings suggest that adults can reduce their likelihood of severe COVID-19–associated outcomes by obtaining a 2025-2026 COVID-19 vaccination.

Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or prevent transmission. Now, Yale School of Medicine researchers have taken a significant step toward a genital herpes vaccine that in preclinical models prevented infection.

In a study published June 19 in Science Immunology, researchers evaluated a two-part vaccination against genital herpes. With the technique, the first part — a typical intramuscular injection like you would receive for a flu shot, for example — is followed by the introduction of nanoparticles to the vagina, where herpes infection occurs in women.

The idea is the initial injection “primes” the immune system while the second localized treatment “pulls” immune activity right to where infection takes place. This study extends the original “prime and pull” approach by developing a new nanoparticle that effectively induces local immunity.

“We’ve found that, in preclinical experiments, this approach is a safe way to recruit the right immune cells in the right place to generate protective immunity,” said senior author Akiko Iwasaki, Sterling Professor of Immunobiology at Yale School of Medicine.

A new study from RCSI University of Medicine and Health Sciences demonstrates a novel approach in anticancer vaccine development. Results present the first preclinical evidence to show the efficacy of an mRNA vaccine in targeting neuroblastoma, the deadliest childhood cancer.

A University of California, Riverside-led study of more than 3,200 emergency department (ED) patients across the United States found that while awareness of influenza vaccination is widespread, most adults seen in EDs are not up to date on their annual flu vaccine.

About The Study: This surveillance study found that while antigenically drifted viruses predominated and caused substantial morbidity and mortality, influenza vaccines were associated with a reduced risk of influenza among those who were vaccinated, and recommended antivirals remained effective.

Boosting the uptake of vaccines for some of the world’s most harmful diseases will be the focus of Aberystwyth University experts’ work at an international meeting of the global vaccine community.