New ‘universal vaccine’ technology could protect us from future virus outbreaks
Peer-Reviewed Publication
This September, we're exploring the science behind vaccines. From how they train our immune systems to fight disease to the research shaping their future, vaccines offer an opportunity to discover the science helping protect individuals and communities around the world.
Updates every hour. Last Updated: 21-Oct-2026 04:16 ET (21-Oct-2026 08:16 GMT/UTC)
- A Cambridge-led team has developed a way to engineer better vaccines that could provide broad protection from thousands of variants of viruses - such as coronaviruses or Ebola - in a single vaccine.
- This represents a fundamental new vaccine technology that could prevent future pandemics before they begin.
- The team used the technology to engineer a vaccine designed to protect against a wide range of coronaviruses, including the cause of the COVID pandemic.
- The results of the first-in-human clinical trial of this technology found it is safe and well tolerated.MIT researchers modified the injectable polio vaccine to promote a mucosal immune response, using an adjuvant delivered by lipid nanoparticles. This vaccine could help to achieve polio eradication while avoiding the risks of the oral polio vaccine.
Persistently low rates of COVID-19 vaccination in Black and Hispanic children suggest that parents in these communities tend to be hesitant about the vaccine for their kids, even when they have received it themselves. Through interviews with parents of school-aged children, a new study sheds light on the factors influencing decisions about vaccination. Findings were published in the June issue of the Vaccine: X journal.
A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months – the first vaccine created to protect against the disfiguring skin disease common in tropical regions of the world and gaining ground in the United States. The researcher who led development of the vaccine is the senior author of a New England Journal of Medicine review article published last week describing the difficulties of treating most forms of the disease and reporting that the live vaccine, found to be safe in animals, is expected to be tested in humans later this year.
Pediatric flu vaccines significantly reduce the number of childhood cases of influenza, new research from Harvard Medical School confirms. The findings, published on June 1 in JAMA Pediatrics, show that for every 100 children vaccinated, between nine and 14 fewer children catch the flu.
For years, researchers have been hoping for vaccines that protect people against not just one strain of HIV, but every strain of the quickly mutating virus. This requires a vaccine that coaxes the human body to develop something called broadly-protective antibodies—molecules that recognize a broad range of HIV strains. Now, scientists at Scripps Research and Sweden's Karolinska Institute have developed an experimental vaccine that leads to broadly protective HIV antibodies in every rhesus macaque tested.