New metric predicts the likelihood of amyloid presence and leads the way in early Alzheimer’s detection
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Jun-2025 22:10 ET (19-Jun-2025 02:10 GMT/UTC)
ROCHESTER, N.Y. (May 14, 2025)—Neuroscience technology innovator Cognivue®, today announced a scientific breakthrough with the launch of the Cognivue Amyloid Risk Measure (CARM)*, a novel metric that predicts the likelihood of the presence of amyloid—a key biomarker of Alzheimer’s disease (AD).1 Now available as an optional feature on the Cognivue Clarity® device (based on FDA-cleared technology), CARM represents a significant advancement in the early detection of Alzheimer’s by helping healthcare providers identify those at risk of cognitive impairment, even before symptoms emerge.
Over time, stress and anxiety can build to a point where life’s challenges become overwhelming and cause physical effects. Now, in ACS Applied Materials & Interfaces, researchers report a dental floss pick with a built-in sensor that could monitor stress as part of a daily routine. The device, which accurately senses levels of the stress hormone cortisol in minutes, could help users recognize when it’s time to get help.
In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The therapeutic molecules self-assemble into nanofibers, which bond to the neuron-killing proteins. Now trapped, the toxic proteins can no longer enter neurons and instead harmlessly degrade.
When biting into a chili pepper, you expect a fiery sensation on your tongue. This spiciness is detected because of capsaicinoid compounds. But for some peppers, despite high levels of capsaicinoids, the heat is mysteriously dull. Now, researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have identified three compounds that lessen peppers’ pungency. These results challenge the reliability of the century-old Scoville scale, which traditionally bases its rating on two capsaicinoids.
A new study published in the journal Environmental Science & Technology examined associations between diet, drinking water, and “legacy” PFAS—chemicals that were phased out of production in the US in the 2000s—with blood samples from California residents. PFAS exposure was associated with consumption of seafood, eggs, and brown rice, but fewer other foods than suggested by earlier studies. PFAS levels were elevated among people who lived in areas where these chemicals were detectable in their drinking water supply, but lower than levels found in highly contaminated communities.
After its new extension, which increased its computing power fourfold, the Jean Zay supercomputer is now capable of 125.9 million billion operations per second. Hosted and operated by the CNRS’s Institute for Development and Resources in Intensive Scientific Computing (IDRIS), Jean Zay, which was acquired by the French Grand Équipement National de Calcul Intensif (GENCI), has become one of France’s most powerful supercomputers. The official inauguration of this extension, which was announced by the French President, was held on Tuesday, 13 May 2025.