Enhancing antibody therapies with polyphenol-conjugated nanocarriers for breast cancer
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Aug-2025 13:11 ET (21-Aug-2025 17:11 GMT/UTC)
In a significant step towards improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier system that delivers therapeutic antibodies directly to target antigens inside cancer cells. By utilizing a metal-polyphenol network, the system escapes endosomes, enabling intracellular targeting of antibodies, resulting in suppression of tumor growth and enhanced anti-cancer activity, offering a promising tool for targeted cancer therapy.
To simulate blood flow inside brain aneurysms, researchers from Japan developed a computational method that combines 4D flow MRI, computational fluid dynamics, and data assimilation, which provides greater accuracy and efficiency. By focusing only on the aneurysm region, this approach significantly reduces computational cost while improving flow estimation. When validated on patient data, it outperforms conventional models—offering a practical tool for patient-specific risk assessment and treatment strategies.
A review has explored the pathways, business models and drivers for youth employment in Africa’s agricultural sector by gaining research and insights from young people and stakeholders involved in youth empowerment activities in Uganda.
The CABI-led review, published in the journal CABI Agriculture and Bioscience, identified six key employment pathways: primary production, agri-service provision, market facilitation, value addition, agro dealership, and green entrepreneurship.
Researchers have demonstrated that by using argon plasma, metal atoms can be dispersed and guided to desired positions. This new strategy ensures that not a single atom goes to waste and maximises the use of rare and precious metals.
In a recent breakthrough published in Optics & Laser Technology and Infrared Physics & Technology, a research team led by Prof. CHENG Tingqing at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences have introduced a novel low-thermal-effect gradient-doped crystal to tame thermal effects and improve brightness of high-power end-pumped Nd:YAG lasers.