Bioprinting muscle that knows how to align its cells just as in the human body
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Apr-2026 16:16 ET (22-Apr-2026 20:16 GMT/UTC)
Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle remains: real muscle is not just a mass of cells. Its strength and function depend on exquisitely ordered myofibers, all aligned in precise directions that vary from one muscle to another. Reproducing that internal order has proved far harder than shaping muscle tissue into the right external form.
In the International Journal of Extreme Manufacturing, a research team from Xi'an Jiaotong University has now found a way to solve both problems at once. By using electric forces during the electrohydrodynamic bioprinting process, they have created living muscle tissues whose cells naturally line up just as they do in the human body, showing how electric forces can be used not just to precisely bioprint tissue, but to quietly instruct cells how to organize themselves.
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