A spatially programmable microfluidic chip for multi-stage particle and cell separation
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Oct-2026 15:16 ET (28-Oct-2026 19:16 GMT/UTC)
A programmable microfluidic device developed at Institute of Science Tokyo, Japan, combines deterministic lateral displacement, a microfluidic technique that is used to separate particles according to their size, with temperature-responsive polymer micropillars to dynamically change the separation conditions along a single channel. Using this device, the researchers successfully separated multiple particle populations. Additionally, they efficiently isolated viable cancer cells, white blood cells, and red blood cells from diluted whole blood.
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