NWPU develops engineered platelets-based nano-aircraft systems for precise tumor chemoimmunotherapy with graded drug delivery and self-recognized tumor targeting
Peer-Reviewed Publication
Updates every hour. Last Updated: 12-May-2025 18:09 ET (12-May-2025 22:09 GMT/UTC)
A research team led by Prof. Liangliang Dai of Northwestern Polytechnical University (NWPU) has launched a platelets-based drug delivery system. The study was published in Science Bulletin.
Metastasis and heterogeneity pose major challenges in cancer treatment. Although chemoimmunotherapy shows promising efficacy, its therapeutic impact is limited by off-target effects and differences in the delivery sites of chemotherapeutic drugs and immunosuppressants. To overcome the limitation, the research team proposed an engineered platelets (Pts)-based nano-aircraft, Pts@DOX/HANGs@Gal, was constructed with an internally loaded chemotherapeutic drug, doxorubicin, and externally grafted reduction-responsive hyaluronidase-cross-linked nanospheroids loaded with the immunosuppressant galunisertib for precise tumor chemo-immunotherapy.
Researchers from the University of Science and Technology of China have uncovered the electrodissolution mechanism of zinc electrodes in aqueous zinc-based batteries, providing new insights for improving zinc electrode reversibility. The findings were published in Science Bulletin under the title "Electrodissolution-Driven Enhancement in Zn Electrode Reversibility."
Researchers to showcase research into neonatal brain repair at the PREMSTEM Conference from 13 to 15 May 2025 in Barcelona, Spain.
Some of the world’s most advanced AI systems struggle to tell the time and work out dates on calendars, a study suggests.
Researchers unveils organic–inorganic interaction sites in non-hydrogen-bonded hybrid perovskite.