Lighting the way: how activated gold reveals drug movement in the body
Peer-Reviewed Publication
Updates every hour. Last Updated: 12-May-2025 15:09 ET (12-May-2025 19:09 GMT/UTC)
Tracking targeted drug delivery is often a challenge due to limitations in the current imaging techniques. A recent study by Tokyo’s Waseda University reports a breakthrough imaging technique that allows direct and highly sensitive tracking of gold nanoparticles (AuNPs) inside the body. This novel technique, which uses neutron activation of gold, could revolutionize cancer drug delivery by enabling real-time visualization of the gold nanoparticles without external tracers.
Researchers from Hong Kong and the UK have developed a novel method for creating quantum holograms using metasurfaces, as detailed in a recent study published in Advanced Photonics. By combining metasurfaces with nonlinear crystals, they achieved entanglement of polarization and holographic information. This innovative approach allows for the generation of quantum holograms, where specific holographic letters can be selectively erased by adjusting the polarization of entangled photons. The study demonstrates the potential of metasurfaces to enhance quantum communication and anti-counterfeiting technologies, offering a compact and flexible alternative to conventional materials. This breakthrough not only advances our understanding of quantum mechanics but also paves the way for practical applications in quantum information processing.
Researchers from the University of Colorado Anschutz Medical Campus studied a new method to deliver antibiotics, specifically gentamicin, directly into the bladder tissue to better treat UTIs. They did this by creating nanogels combined with a special peptide (a small protein) that helps the drug get inside the cells where the bacteria are hiding.
The results, published in Nanomedicine, demonstrate that this approach proved highly effective when tested in animal models with UTIs, eliminating over 90% of the bacteria from the bladder.
“We prove not only that this technology is doable but could be very effective for future clinical use and can potentially lead towards an eventual cure of recurrent infections,” said the paper’s senior author Michael Schurr, PhD, associate professor in the Department of Immunology & Microbiology at the University of Colorado School of Medicine.
The researchers discovered that nanogel technology can carry more than enough gentamicin to be effective - about 36% more gentamicin inside cells compared to standard antibiotic delivery methods. Additionally, it exhibits low toxicity, causing minimal harm to cells.
They also found that nanogels release the drug quickly, which helps kill bacteria in the bladder faster.
A new study published in Engineering reviews the latest research in tissue engineering for spinal cord injury (SCI) repair. It explores the roles of biomaterials, cells, dECM, exosomes, and other factors. Although more research is needed, these findings offer new directions for SCI treatment.
A new review in Engineering explores the intricate links among food systems, climate change, and air pollution. It reveals how these elements impact one another and details strategies to mitigate their effects and build a more sustainable future for food security and the environment.