Cellular metabolism plays a critical role in various physiological and pathological processes. High resolution imaging of intracellular metabolic activities is crucial for understanding many biological pathways, and for facilitating disease prognosis and treatment assessment. Raman scattering (RS) spectroscopy/microscopy, in particular stimulated Raman scattering (SRS), has emerged as a powerful imaging technology for cellular imaging with high specificity, high sensitivity, and subcellular resolution. Since its invention, SRS microscopy imaging has been extensively applied in life science for studying composition, structure, metabolism, development, and disease in biological systems. This review focuses on the latest applications of SRS imaging, particularly with heavy water probing, for studying metabolic dynamics of biomolecules in organisms during aging and diseases. Furthermore, future applications and development of SRS imaging in both life science and medicine are considered.

Simulations of quantum many-body problems are a challenge for even the most powerful conventional computers. Quantum computing has the potential to solve this challenge using an approach called an analog quantum simulation. To succeed, these simulations need theoretical approximations of how quantum computers represent many-body systems. In this research, nuclear physicists developed a new framework to analyze these approximations and minimize their effects.

A new fully automated in vivo screening system (AISS) has been developed to transform drug evaluation by enabling rapid, precise, and non-invasive multi-organ imaging in zebrafish. Integrating cutting-edge microfluidic technology with computer-vision-based control, this innovative system automates every aspect of zebrafish larvae handling— from loading and encapsulation to immobilization and drug exposure.