Chronic diabetic wounds heal slowly and are highly vulnerable to infection. Researchers have developed an AI-guided, 4D-printed microneedle patch that actively closes wounds, fights bacteria, and promotes tissue repair. Inspired by the carnivorous plant Drosera capensis, the device combines shape-changing materials, adhesive DNA nanoparticles, and antibacterial zinc treatment, demonstrating how AI can transform biological inspiration into programmable medical technology.

As digital twins expand across fields ranging from healthcare to climate forecasting, concerns about privacy, cybersecurity, and transparency are also growing. A review of nearly 22,500 publications argues that digital twins should be understood as decision infrastructures that integrate sensing, modeling, artificial intelligence, and data systems to support smarter, more explainable, and secure decisions in complex real-world settings

Non-line-of-sight (NLOS) imaging enables recovery of hidden scenes but is constrained by a speed-resolution trade-off in conventional scanning systems. We propose a scanning-free approach based on laser reflective tomography, using a diffuse relay surface as a natural beam expander and requiring only single-point detection. This method achieves twofold higher resolution and 91-fold faster imaging, and enables 3.3 km long-range reconstruction with 3 cm resolution in just 3 minutes.

A recent study identified carbonic anhydrase III (CAR3) as a previously unrecognized protein critical for healthy bone development and regeneration. Using single-cell RNA sequencing, genetically modified mice, and bone repair models, researchers found that CAR3 helps osteoblasts mineralize collagen and strengthen bone tissue by interacting with collagen and bone sialoprotein. Mice lacking CAR3 developed low bone density and impaired bone formation, while CAR3-functionalized scaffolds significantly improved bone healing and regeneration following skeletal injury.

Nanomedicines often acquire a protein corona in the bloodstream before reaching the brain. A new Perspective in Science Bulletin argues that this evolving layer should be engineered as a programmable interface that can guide recognition, transcytosis and release across the blood-brain barrier.