Researchers have developed a new method to more accurately analyze small microplastics in the ocean. They collected seawater from 12 ocean layers across 4 regions in the North Pacific Ocean to find that the concentrations of small microplastics ranged from 1,000 to 10,000 particles per cubic meter of seawater. Additionally, small microplastics enter the ocean by either reaching near-neutral buoyancy to drift at specific depths or rapidly sink to the seafloor.

Organoid research has rapidly advanced as a transformative platform for modeling development, disease, and regeneration, yet inconsistent reporting has hindered reproducibility and limited data integration across laboratories. The newly introduced Minimum Information about Organoid Research (MIOR) framework establishes a comprehensive, modular reporting system designed to address these challenges. MIOR defines clear requirements for project metadata, biological sources, organoid characterization, culture conditions, engineering strategies, and assay parameters. By distinguishing essential from recommended fields, the framework balances rigor with practical usability. MIOR aims to turn organoid datasets into reusable, comparable resources and strengthen the reliability and translational potential of organoid-based research.

Insilico Medicine (“Insilico”), a clinical-stage, generative AI-driven drug discovery company, today announced its participation in NeurIPS 2025, to be held in San Diego, USA, from December 2–7, 2025. Led by Alex Zhavoronkov, PhD, Founder and CEO of Insilico Medicine, and Petrina Kamya, PhD, Global Head of AI Platforms, Insilico’s experienced team will participate in the conference.

In a recent pioneering study, researchers at Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage biotechnology company, harnessed its AI-driven generative chemistry platform, Chemistry42, to design a novel, first-in-class PROTAC targeting PKMYT1, D16-M1P2, which employs a dual mechanism of action—inducing PKMYT1 degradation while directly inhibiting its kinase activity. This innovative strategy holds promise for overcoming limitations of existing inhibitors, such as poor selectivity and acquired resistance, and to effectively target both the catalytic and non-catalytic functions of PKMYT1. As a result, the PROTAC demonstrates the potential for a more selective, potent, and durable therapeutic effect.

An international research team led by RMIT University have created tiny particles, known as nanodots, made from a metallic compound that can kill cancer cells while leaving healthy cells largely unharmed.

While this work is still at the cell-culture stage – it hasn’t been tested in animals or people – it points to a new strategy for designing cancer treatments that exploit cancer’s own weaknesses.

How far is it really from Hamburg to Rome – by ship, train, or truck? A research team including KLU Professor Arne Heinold has found a way to answer that question within milliseconds using open data. Their work was awarded the 2025 Prize for Open Data from the renowned American research institute, the Massachusetts Institute of Technology (MIT).

Quantum computers will be able to assume highly complex tasks in the future. With superconducting quantum processors, however, it has thus far been difficult to read out experimental results because measurements can cause interfering quantum state transitions. Researchers at Karlsruhe Institute of Technology (KIT) and Université de Sherbrooke in Québec have performed experiments that improve our understanding of these processes and have shown that calibrating the charge at the qubits contributes to fault avoidance. Their findings have been published in Physical Review Letters. (DOI: 10.1103/yljv-b4kj[SW1)

Using catalytic chemistry, researchers at Institute of Science Tokyo have achieved dynamic control of artificial membranes, enabling life-like membrane behavior. By employing an artificial metalloenzyme that performs a ring-closing metathesis reaction, the team induced the disappearance of phase-separated domains as well as membrane division in artificial membranes, imitating the dynamic behavior of natural biological membranes. This transformative research marks a milestone in synthetic cell technologies, paving the way for innovative therapeutic breakthroughs.