Targeting osteoclastogenesis: Egg yolk hydrolysate exhibits inhibitory effects
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Dec-2025 17:11 ET (20-Dec-2025 22:11 GMT/UTC)
Egg yolk, long known for its nutritional benefits, may hold the key to a natural treatment for osteoporosis. A groundbreaking study has found that water-soluble egg yolk fractions, particularly the FC1 subfraction (< 3 kDa), significantly inhibit osteoclastogenesis—the process responsible for bone resorption. This discovery, based on in vitro tests with RAW264.7 macrophages, shows that FC1 not only curbs osteoclast formation but also activates apoptosis in mature osteoclasts. With further research, these egg yolk-derived bioactive compounds could pave the way for safer, natural supplements to promote bone health, offering an alternative to traditional treatments with fewer side effects.
Fermented sausages are renowned for their bold, region-specific flavors—but what truly drives these sensory profiles lies beneath the surface. This review uncovers how dynamic microbial successions shape flavor development in both Eastern and Western sausage varieties. While Western sausages such as salami and chorizo rely on controlled fermentation with selected starter cultures for consistency, Eastern sausages depend on spontaneous microbial activity and local ingredients, resulting in diverse and nuanced flavors. By revealing the biochemical and microbial pathways responsible for taste formation, the study offers new insights into improving quality, safety, and flavor optimization for global consumers.
Researchers are set to shine a different kind of light on the farming industry after receiving funding to explore how fluorescent materials used in TV and phone screens can detect the presence of pesticides and herbicides in food production.
A new study combines eye tracking and artificial intelligence to identify the exact moments in an educational video that matter for learning in children. The study could also predict how much children understood from the video based on their eye movements while they were watching it.
- KAIST–Stanford University collaborative study reveals how ethane alters core metabolism in obligate methanotrophs
- Ethane addition suppresses cell growth, reduces methane consumption, and boosts PHB synthesis
- Offers a new understanding of methanotrophic metabolism in mixed-gas environments and its potential for sustainable biopolymer production
KAIST announced that a research team led by Professor Jaewook Myung from the Department of Civil and Environmental Engineering, in collaboration with Stanford University, has identified how ethane (C2H6)—a major constituent of natural gas—affects the core metabolic pathways of the obligate methanotroph Methylosinus trichosporium OB3b.
Targeted drug delivery to tumors is crucial for effective and safe treatment of cancer. In a recent breakthrough, researchers from Okayama University have developed a pH-responsive nanomaterial using graphene oxide and polyglycerol for cancer drug delivery. The surface of the developed nanomaterial changes its charge in an acidic tumor environment and enables uptake of drugs by cancer cells while avoiding immune clearance. This innovative approach opens doors to precision-driven and more efficient cancer therapies.