A new study by researchers at the Icahn School of Medicine at Mount Sinai overturns a longstanding assumption about how mRNA vaccines generate immunity, revealing that certain non-immune cells help determine vaccine effectiveness. The study, published in the April 29, 2026 online issue of Nature Biotechnology https://doi.org/10.1038/s41587-026-03099-z], also introduces a powerful and versatile technology to control the expression of mRNA drugs, which the researchers demonstrate can enhance the effectiveness of mRNA cancer vaccines in preclinical studies of lymphoma. The findings provide a new framework for designing mRNA vaccines and mRNA therapeutics, with immediate implications for cancer immunotherapy, infectious disease vaccines, and gene-editing treatments.

The platform integrates multi-omic data to drive both biomedical research and clinical practice.

Its technology, based on Graph Foundation Models, extracts robust conclusions even from the limited and heterogeneous samples typical of the biomedical field.

Variable-load unmanned aerial vehicles (UAVs) are key tools in smart agriculture, particularly playing a vital role in the prevention and control of crop pests and diseases. Equipped with pesticide spraying equipment, these quadrotor UAVs offer advantages such as high operating speed, low risk of chemical drift, and improved crop coverage, making them widely used in agricultural plant protection.