Pulse oximeter index offers non-invasive guides for fluid therapy
Peer-Reviewed Publication
Updates every hour. Last Updated: 6-Nov-2025 20:11 ET (7-Nov-2025 01:11 GMT/UTC)
A new study from Avicenna University Hospital in Marrakesh demonstrates that the plethysmographic perfusion index (PPI), a non-invasive measure derived from standard pulse oximeters, can help guide fluid therapy in critically ill patients with acute circulatory failure. Using a 500-mL fluid challenge in 50 ICU patients, researchers found that changes in PPI after the bolus accurately identified those likely to benefit from additional fluids, offering a low-cost, accessible tool for safer resuscitation.
Regular follow-up is necessary after endovascular aneurysm repair to detect possible endoleaks. In a recent breakthrough, researchers from Hanyang University have recently developed a novel ultrathin, flexible, wireless, and implantable sensor for continuous monitoring of blood leakage. Their technology has the potential to become the new standard of care for aneurysm treatment, enabling timely intervention and highly enhanced postoperative outcomes.
A research team has successfully engineered yeast cell factories to selectively secrete and produce vitamin A (retinoids), achieving record yields of retinol, retinal, and retinoic acid.
Researchers at the Icahn School of Medicine at Mount Sinai and their collaborators have developed a new technology to track beneficial bacteria after fecal microbiota transplants (FMT). The approach provides a detailed view of how donor microbes take hold and persist in the patients’ gut—not only which bacteria successfully colonized but how they change over time. These insights may guide the design of safer and more effective microbiome-based therapies. The study was published in the October 22 online issue of Nature Microbiology [DOI: https://doi.org/10.1038/s41564-025-02164-8].
People living, working and visiting London, UK have seen substantial reductions in air pollution following the introduction of the Ultra Low Emissions Zone (ULEZ) introduced in 2019, according to a new research paper published in a study published in npj Clean Air today (Weds 22 October).