31-May-2015 Delirium can lead to longer hospitalizations and shorten the life of ICU patients D'Or Institute for Research and Education Peer-Reviewed Publication A major systematic review of published studies conducted by scientists from Brazil and USA indicates a robust association between delirium in ICU and adverse health outcomes. The research shows that delirium can shorten the life of patients, lead to longer stays at the hospital and cause post-discharge cognitive impairment. Journal The BMJ
11-May-2015 A tale of two roads into protein unfolding Publicase International Peer-Reviewed Publication Researchers have used physical and chemical strategies to force proteins into unfolding but only now a new study reveals how exactly they work, with potential implications for a number of age-related diseases including Parkinson's, Alzheimer's, Huntington's and even cancer. Journal Proceedings of the National Academy of Sciences Funder Ministry Of Health, Carlos Chagas Filho Foundation for Research Support in the State of Rio de Janeiro, National Council for Scientific and Technological Development
30-Apr-2015 Fossils inform marine conservation Smithsonian Tropical Research Institute Peer-Reviewed Publication Fossils help predict which animals are likely to go extinct. Scientists combine information from the fossil record with information about hotspots of human impact to pinpoint animal groups and geographic areas of highest concern for marine conservation. Journal Science Funder National Evolutionary Synthesis Center, Panama's National Secretariat for Science, Technology and Innovation, Australian Research Council and others, National Science Foundation, Natural Sciences and Engineering Research Council of Canada
28-Apr-2015 Ancient connection between the Americas enhanced extreme biodiversity Smithsonian Tropical Research Institute Peer-Reviewed Publication Species migrations across the Isthmus of Panama began about 20 million years ago, some six times earlier than commonly assumed, a new study by Smithsonian scientists and colleagues published this week in the Proceedings of the National Academy of Sciences shows. Journal Proceedings of the National Academy of Sciences Funder Ricardo Perez, Autoridad del Canal de Panama, Mark Tupper Smithsonian Fellowship, Smithsonian Institution, Wenner-Gren and Carl Tryggers Foundations, National Science Foundation, European Research Council and others, Swedish Research Council, S.A.
22-Apr-2015 To predict disease researchers ask if plant neighbors are relatives Smithsonian Tropical Research Institute Peer-Reviewed Publication Disease shapes plant communities and determines the outcomes of environmental change, weed invasions and agriculture and forestry management strategies. Whether or not a disease devastates a plant community depends on how related the plant species are and on how many individual plants of each species are present. Journal Nature Funder National Science Foundation, US Department of Agriculture
20-Apr-2015 Necessity at the roots of innovation: The scramble for nutrients intensifies as soils age Smithsonian Tropical Research Institute Peer-Reviewed Publication Working among venomous snakes in Australia's Jurien Dunes, researchers ask how biodiverse plants survive in some of the world's worst soils. Their discoveries may help to develop agriculture on poor soils elsewhere. Journal Nature Funder Australian Research Council, UWA
13-Apr-2015 Brazilian study suggests adjustments on the treatment of cancer patients with pneumonia D'Or Institute for Research and Education Peer-Reviewed Publication Pneumonia is the most frequent type of infection in cancer patients and it is associated with high mortality rates. Brazilian researchers analyzed the factors associated with severe pneumonia in hospitalized cancer patients and suggest that personalized treatment protocols can reduce mortality in this population. Their work indicates that the standard broad-spectrum antibiotic treatment used by physicians worldwide may not be the better choice for this group. Journal PLOS One
12-Apr-2015 Report on Bioenergy and Sustainability to be launched Fundação de Amparo à Pesquisa do Estado de São Paulo Book Announcement More than 100 experts from around the world contributed to the report, which presents main findings and recommendations on current production and use of bioenergy, as well as growth potential, considering such aspects as land use, feedstocks, technologies, impacts and policies. Funder São PAulo Research Foundation, Scientific Committee on Problems of the Environment
9-Apr-2015 Smithsonian's Panama debate fueled by zircon dating Smithsonian Tropical Research Institute Peer-Reviewed Publication New evidence published in Science by Smithsonian geologists dates the closure of an ancient seaway at 13 to 15 million years ago and challenges accepted theories about the rise of the Isthmus of Panama and its impact on world climate and animal migrations. Journal Science
3-Apr-2015 Possible progress against Parkinson's and good news for stem cell therapies D'Or Institute for Research and Education Peer-Reviewed Publication Researchers at D'Or Institute for Research and Education and Federal University of Rio de Janeiro have taken an important step toward using the implantation of stem cell-generated neurons as a treatment for Parkinson's disease. Using an FDA approved substance for treating cancer, they were able to grow dopamine-producing neurons derived from embryonic stem cells that remained healthy and functional for as long as 15 months after implantation into mice, restoring motor function without forming tumors. Journal Frontiers in Cellular Neuroscience