A study recently published in the scientific Journal Neurobiology of Aging, developed in partnership between researchers from L’Oréal Brasil, the D’Or Institute for Research and Education (IDOR), UFRJ and EPISKIN, advanced in the understanding of changes in skin physiology over the years and the consequent loss of skin sensoriality. The research, carried out with a model of human reconstructed skin RHE from EPISKIN, showed that the formation of aggregates of proteins already known to degenerate neurons, contributes to skin aging.