Increased extracellular matrix (ECM) stiffness, a hallmark of risk in cardiovascular disease (CVD), is closely associated with inflammation triggered by immune cell infiltration in the vessel wall.

With the rapid revolution in super-resolution microscopy, the resolution of far-field optical microscopy has entered the sub-nanometer era, providing new insights into macromolecules in vitro and in situ.

The intricate structure of the brain at various scales is linked to its functional and biomechanical properties. Since understanding the biomechanical properties is vital for comprehending brain diseases, development, and injuries, measurements at different scales are necessary.

α-Synuclein (α-Syn) is a presynaptic protein primarily associated with Parkinson’s disease and other neurodegenerative diseases.

ATP-sensitive potassium (K_ATP) channels are integral components in excitable cells, particularly in cardiomyocytes, serving as critical regulators of cellular metabolism and electrical excitability.

A Canadian team turned 23,000 mating types into a materials library, showing nuclear-mitochondrial combos double film strength or ductility depending on cross-linker choice.

Writing in the Journal of Bioresources and Bioproducts, researchers report the first systematic screen of wild fungal genotypes for pure mycelial materials, proving that strain choice can outperform process tweaks in green fabrication.

Engineers have merged neomycin-grafted cellulose nonwovens with a polyvinyl-alcohol/cellulose-nanofiber aerogel to create a biodegradable smart bandage that delivers >99 % kill of Staphylococcus aureus and Escherichia coli within 30 min, scavenges 93 % of free radicals and produces –1.4 mmHg micro-negative pressure to pull exudate away from chronic lesions. Reporting in the Journal of Bioresources and Bioproducts (2025, 10, 373-385) the team show that blueberry-derived anthocyanins embedded in the matrix act as a built-in pH sensor, shifting colour when infection drives wound alkalinity above pH 8. In a murine full-thickness infection model the dressing closed 88 % of wound area in seven days, outperforming a leading commercial dressing and suppressing inflammatory IL-1β and TNF-α expression to baseline levels. Complete soil burial disintegrates the device within 90 days, offering a plastic-free route to connected wound care.