Beyond oxidative damage: Reactive Oxygen Species (ROS) are essential for ordered plant development—ROS-producing enzymes coordinate cell proliferation, tissue integrity, and differentiation
Peer-Reviewed Publication
Updates every hour. Last Updated: 31-Oct-2026 03:16 ET (31-Oct-2026 07:16 GMT/UTC)
Reactive oxygen species (ROS) are often linked with oxidative damage. However, they are essential for cell signalling. A new study highlights their crucial role in plant development and morphogenesis. Using the liverwort Marchantia polymorpha, researchers found that disrupting the two genes responsible for producing ROS molecules led to disrupted plant growth and formation of disordered cellular masses. The study reveals a fundamental mechanism connecting cell division, tissue structure, and plant development.
The academic significance of this study has been highly recognized internationally, as evidenced by the simultaneous publication of a highlighted Dispatch article in the same journal by Professor Christine Foyer (University of Edinburgh, UK), a world-leading authority in plant reactive oxygen research.
Plant development: RBOH genes
https://www.sciencedirect.com/science/article/pii/S0960982226004641
A recent study identified carbonic anhydrase III (CAR3) as a previously unrecognized protein critical for healthy bone development and regeneration. Using single-cell RNA sequencing, genetically modified mice, and bone repair models, researchers found that CAR3 helps osteoblasts mineralize collagen and strengthen bone tissue by interacting with collagen and bone sialoprotein. Mice lacking CAR3 developed low bone density and impaired bone formation, while CAR3-functionalized scaffolds significantly improved bone healing and regeneration following skeletal injury.
A new study has uncovered a previously unknown antiviral defense mechanism in sea anemones, revealing that animals may have evolved more than one way to fight viral infections. Researchers discovered that a protein resembling a key component of the human immune system actually plays the opposite role, yet remains essential for effective antiviral protection. The findings challenge assumptions about the evolution of immunity and suggest that fundamentally different antiviral strategies have emerged across the animal kingdom.
Salk scientists explore long-standing mystery of why iron that builds up in neuronal cells becomes harmful over time in neurodegenerative diseases like Alzheimer’s and Parkinson’s, finding a new cellular process, named chronoferroptosis, wherein chronic iron dysregulation in neurons makes them more vulnerable to stressors. The study complements other ongoing research at Salk to design compounds that inhibit this pathway, and could be a promising future avenue for creating therapies that boost resilience in aging brains.