Scientists build first genetic "toggle switch" for plants, paving the way for smarter farming
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Updates every hour. Last Updated: 20-Jun-2025 16:10 ET (20-Jun-2025 20:10 GMT/UTC)
Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain’s natural waste drainage system—a discovery that could open new avenues for tackling age-related neurological disorders.
In a study published in Nature, researchers from the IBS Center for Vascular Research, led by Director KOH Gou Young, along with senior researchers JIN Hokyung, YOON Jin-Hui, and principal researcher HONG Seon Pyo, demonstrated that precisely stimulating the lymphatics under skin on the neck and face can significantly enhance the flow of cerebrospinal fluid (CSF)—the liquid that cushions the brain and helps remove toxic waste—through lymphatic vessels. This offers a new approach to clearing brain waste using safe, non-invasive mechanical stimulation, rather than relying on drugs or surgical interventions.What if your brain had a built-in map – not of places, but of possible futures? Researchers at the Champalimaud Foundation (CF) blend neuroscience and artificial intelligence (AI) to reveal that populations of dopamine neurons in the brain don’t just track whether rewards are coming – they encode maps of when those rewards might arrive and how big they might be.
These maps adapt to context and may help explain how we weigh risks, and why some of us act on impulse while others hold back. Strikingly, this biological mechanism mirrors recent advances in AI, and could inspire new ways for machines to predict, evaluate and adapt to uncertain environments more like we do.
The development of ferroptosis-based nanotherapeutics is generally limited by poor penetration depth into tumors and potential systemic toxicity.
In a recent issue of International Journal of Extreme Manufacturing, Tu and coworkers from Southern Medical University addressed these challenges by proposing the design and fabrication of self-propelled ferroptosis nanoinducers, composed of only two endogenous proteins with natural bioactivity.
This work offers a strategy for constructing a biocompatible cancer treatment paradigm with enhanced diffusion to achieve deeper penetration into tumor tissues, centered around the concept of ferroptosis.