Not only do big dogs die younger but they are also more susceptible to many age-related diseases. And what scientists can learn about dog aging can provide an important window into human aging too. 

Now we may know why. 

A new study led by researchers at Arizona State University offers the first compelling molecular explanation of why large dogs live shorter lives: the answer may lie in how hallmarks of aging reshape dog DNA. 

Researchers successfully built a time-calibrated lineage tree showing how a single cell turned into 1.28 million—about 10% of the cells in a two-week-old mouse embryo. This is by far the largest lineage tree ever built for a mammal.

Majestic African antelopes known as gemsbok have been roaming the U.S. southwest since their introduction in the 1960s and 1970s. Brought to New Mexico as game species for hunting, gemsbok quickly settled in, expanding more than 100 kilometers from their introduction point. University of Illinois Urbana-Champaign researchers say that’s due to their exceptional adaptations to arid conditions, which they predict will dramatically expand under climate change.

Understanding how this nitrogenase functions could have huge implications for the more efficient and biologically-based production of ammonia, a crucial component of common fertilizers.

OpenCGChromatin allows researchers to simulate how chromatin is organised and moves in fine molecular detail.

Published in Nature Communications, the study is a collaboration between IRB Barcelona, the University of Cambridge, UT Southwestern Medical Centre and the Howard Hughes Medical Institute.

Researchers from the Department of Cell Biology, Genetics and Physiology at the University of Malaga have led an international scientific team that has studied how a traumatic brain injury caused by a severe blow to the head conditions the brain’s long-term response to subsequent stress situations.

Wild African savannah elephants use a wide range of gestures when competing with other elephants, according to research from a group of international scientists including from the University of Portsmouth, University of Vienna and University of St Andrews.

Researchers at Inner Mongolia University of Science and Technology and collaborators developed AHormoneDB, a cross-species hormone knowledge base that integrates multi-omics data, regulatory prediction, and retrieval-augmented natural-language queries. The platform contains 7,833 standardized hormone–gene–disease evidence records, and its GeneReg v2.6 module achieved an F1-score of 0.894 on an internal test set. In an acromegaly case study, AHormoneDB nominated PTPN1 as a previously underappreciated candidate node for further investigation.