Aneuploidy—the presence of an incorrect number of chromosomes—is common during the normal development of human embryos and is the main cause of spontaneous miscarriage.

A team of researchers at IRB Barcelona has developed a genetic tool to create customized aneuploidies and analyse their impact during development.

Published in Cell Genomics, the study demonstrates that aneuploid cells are actively eliminated by neighbouring cells through cell competition.

These mechanisms may be involved in the removal of aneuploid cells during early human development.

Researchers at Swansea University have discovered that baboons walk in lines, not for safety or strategy, but simply to stay close to their friends.

Herpes simplex virus type 1 (HSV-1) infections can lead to deadly brain inflammation, yet treatment options remain limited. Japanese researchers have now uncovered how HSV-1 evades the host’s intrinsic immunity by using an enzyme, uracil-DNA glycosylase, to block APOBEC1, a host protein that edits viral DNA to suppress infection. They also developed a promising therapeutic strategy to restore immune defense in the brain, offering new hope for managing HSV-1-induced encephalitis.