BUFFALO, NY - March 25, 2025 – A new review was published in Oncotarget, Volume 16, on March 13, 2025, titled “Signaling pathway dysregulation in breast cancer."

Scientists at the Woods Hole Oceanographic Institution (WHOI), in collaboration with international partners, have developed a novel approach to addressing uncertainties in ecological and environmental projections, providing a more robust assessment of extinction risk for emperor penguins. The study, which accounts for the unique life history and critical dependence of emperor penguins on the Antarctic environment, reveals that emperor penguins meet the criteria for uplisting to a category ranging from Vulnerable to Endangered under the IUCN guidelines on risk and uncertainty (IUCN, 2024). This represents a significant and urgent change from their current classification of Near Threatened, highlighting the elevated risk emperor penguins face due to future changes in their Antarctic habitat.

A new study in Forest Ecosystems unveils innovative design strategies to dramatically improve Pinus tabuliformis, a cornerstone species of northern China's forests. The research focused on optimizing advanced generation breeding, revealing that direct selection significantly outperforms combined selection, delivering impressive gains: a 7.72% increase in diameter, a substantial 18.56% jump in height, and a remarkable 31.01% surge in overall volume. Furthermore, addressing the critical issue of inbreeding, the researchers developed the Improved Adaptive Genetic Programming Algorithm (IAPGA). This innovative strategy demonstrably reduces inbreeding by a significant 14.36% within advanced seed orchards established using the selected breeding population. The results are pivotal for sustainable forest management, promising enhanced ecological resilience and substantial economic benefits through increased timber yield and improved forest health. This study provides valuable insights for optimizing breeding programs and ensuring the long-term vitality of Pinus tabuliformis forests in China.

Enzymes originally evolved in high-temperature environments and later adapted to lower temperatures as Earth cooled. Scientists from Waseda University and RIKEN, Japan, discovered that a key shift in enzyme function occurred over evolutionary time due to amino acid changes distant from the active site. These mutations lowered activation energy, enhancing catalytic efficiency at low temperatures. Their findings highlight how global cooling events influenced enzyme evolution.

In some countries, the number of dogs has increased so much that it now exceeds the number of children. While the emotional significance of dogs is clearly rising worldwide, it remains uncertain whether people are choosing to keep dogs instead of having children or whether other factors are driving this trend. Professor Enikő Kubinyi, head of the Department of Ethology at Eötvös Loránd University (ELTE), has proposed a groundbreaking theory in one of the world's leading psychology journals. According to her, there is indeed a connection between dog ownership and declining birth rates — but not in the way we might think.

Our comprehensive search suggests that venom delivery systems fully analogous to those of animals exist among plants, fungi, protists, bacteria, and viruses. Thus, venomous organisms are far more diverse than previously recognized.