COP6 decision on dental amalgam secures an equity-focused, patient-centred approach
Reports and Proceedings
Updates every hour. Last Updated: 22-Dec-2025 09:11 ET (22-Dec-2025 14:11 GMT/UTC)
Geneva, Switzerland — A landmark decision was reached at the Sixth Conference of the Parties (COP6) to the Minamata Convention on Mercury, where Parties agreed to set 2034 as the global phase-out date after which the manufacture, import, or export of dental amalgam will no longer be permitted. This milestone marks a major win for oral and public health and underscores the power of unified, science-based advocacy led by FDI World Dental Federation (FDI) and the International Association for Dental, Oral, and Craniofacial Research (IADR).
FAU’s “Art of Science” contest turns research into stunning visual stories. The top image, “First Selfie … Cephie,” shows an octopus seemingly posing for a camera, showcasing its incredible dexterity. Other top winners are the “Sea Turtle Beginning,” capturing embryonic development inside an egg, and “Journey to Space,” a high-altitude balloon bursting nearly 100,000 feet above Earth. The contest celebrates creativity across science, art, and the community, revealing the hidden beauty and wonder of discovery.
Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, and their attachment differs protein to protein. Researchers aimed to investigate the selectivity of a specific, cancer-related enzyme, N-acetylglucosaminyltransferase-V (GnT-V or MGAT5). GnT-V is often abnormally upregulated and can be an indicator of a poor prognosis in cancer diagnoses, with N-glycans individually associated with diseases such as Alzheimer's, emphysema, diabetes and cancer. Understanding why and how GnT-V selects substrates may offer therapeutic solutions for diseases involving this enzyme.
Cervical cancer, one of the most common malignancies in women worldwide, is primarily driven by human papillomavirus (HPV) infection. Researchers from China have identified a new subtype of keratinocytes, designated as PI3+S100A7+ cells, that appear early in HPV-positive cervical cancer and interact closely with immune cells to promote tumor progression. Using single-cell RNA sequencing, the team discovered how these cells alter the tumor environment and predict poor patient outcomes.
This study reports the first molecular evidence of potentially zoonotic Rickettsia species in ticks collected from domestic dogs in Malawi, marking a significant advancement in understanding tick-borne disease risks in southeastern Africa. Researchers from Hokkaido University and Lilongwe University of Agriculture and Natural Resources screened 209 dog blood samples and 259 tick samples using molecular techniques. While no Rickettsia DNA was detected in dog blood, the analysis revealed infection rates of 2.5% in Rhipicephalus linnaei ticks and 6.3% in Haemaphysalis elliptica ticks.
The study identified three Rickettsia species: Rickettsia conorii subsp. conorii (the causative agent of Mediterranean spotted fever), Rickettsia massiliae, and Rickettsia rhipicephali. Notably, this is the first report of R. massiliae and R. rhipicephali in southern Africa, indicating a geographical expansion of these pathogens. The findings highlight the important role that dog-associated ticks may play in maintaining and transmitting rickettsial pathogens with zoonotic potential.
Given the close association between dogs and humans in Malawi, where people often share living spaces with their pets, these findings underscore the need for integrated One Health surveillance approaches. The research team recommends future studies include human serosurveys and public awareness campaigns to better assess the true burden of rickettsial infections in the region.