How a crucial DNA repair protein works—and what it means for cancer treatment
Peer-Reviewed Publication
Updates every hour. Last Updated: 5-May-2025 17:09 ET (5-May-2025 21:09 GMT/UTC)
DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these proteins—called polymerase theta (Pol-theta)—for their own survival. But scientists at Scripps Research have now captured the first detailed images of Pol-theta in action, revealing the molecular processes responsible for a range of cancers.
Researchers at the University of Calgary are suggesting a more comprehensive approach for identifying at-risk wildlife populations — such as caribou — based on individual movement patterns. The paper, published on Feb. 20 in the journal Biological Conservation, uses a long-term dataset of caribou wearing GPS collars across Western Canada. It identifies six distinct behavioural groups that would each deserve their own conservation actions.
A recent review in Engineering explores multi-photon 3D nanoprinting. This technology, with its unique 3D processing and nanoscale resolution, has wide applications in fields like optics and biology. However, it faces challenges such as slow processing speed and material limitations. The article also looks at potential solutions and future development directions, offering insights into the future of this technology in manufacturing.
Adipose tissues, which serve as fat reserves, have been recognized as an endocrine organ. The three-dimensional (3D) bioprinting of adipose tissues has potential applications in regenerative medicine. However, the 3D bioprinting conditions have not been optimized for adipose tissues. Now, researchers from Korea have developed a novel method for 3D adipose tissue bioprinting using a hybrid bioink. The 3D bioprinted adipose tissues exhibited skin regeneration ability, paving the way for their applications in regenerative medicine.