Mononuclear macrophages serve as the primary target cells for the in vivo metabolism of iron-based nanomaterials. The uptake of nanoparticles by mononuclear macrophages is influenced by various factors, such as particle size, surface charge, and administration route, which subsequently affect the metabolic process. During this process, iron-based magnetic nanomaterials can induce macrophage reprogramming and participate in immune modulation. This is primarily reflected in their regulation of macrophage function through enzyme-like activities, intracellular iron metabolism, cell signaling pathways, mitochondrial energy metabolism, and responses to magnetic fields.

Three University of Texas at Arlington faculty members were recognized for their research and creative contributions as part of the faculty research honors. J. Ping Liu, professor of physics, received the University Award for Distinguished Record of Research or Creative Activity. Kyrah Brown, associate professor of kinesiology, and Ben Jones, associate professor of physics, received the University Award for Outstanding Research or Creative Accomplishment.