Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive motor and psychiatric symptoms. Accumulating evidence has implicated mitochondrial dysfunction as a hallmark of PD; however, its underlying mechanisms, and particularly the role of individual mitochondrial complex I subunits in disease pathogenesis, remain poorly understood.

A new study led by Flinders University has flipped the historic narrative about Australia’s thylacine, finding the native apex predator known as the ‘Tasmanian tiger’ was significantly different from the wolves and wild dogs it was likened to before being hunted to extinction.   

In-depth investigations on historic thylacine (Thylacinus cynocephalus) skull specimens indicate their jaws were probably unsuited to holding down large animals like sheep – instead their long, deep jaw would have been able to subdue relatively small prey with powerful snapping bites.

Hederagenin, a plant-derived triterpenoid, reactivates the protective Klotho gene by blocking a key DNA methylation enzyme — revealing a promising epigenetic strategy against diabetic kidney disease.

Astragalus polysaccharide reduces brain injury in mice and in human microbiota-transplanted models by restoring gut health, suppressing inflammation, and strengthening the intestinal barrier.

New recommendations show how aligning EU policies can scale up sponge restoration to reduce flood and drought risks, improve water quality, support biodiversity and build climate resilience.

Menopausal syndrome, also known as perimenopausal syndrome or menopause-related symptom complex, refers to a group of symptoms that occur as ovarian function gradually declines under natural physiological conditions. These symptoms are mainly related to autonomic nervous system dysfunction and neuropsychological changes, including hot flashes, night sweats, sleep disorders, anxiety, and depression. With increasing life expectancy, women are spending a longer period of their lives after menopause. As a result, perimenopausal health management is no longer limited to short-term symptom relief, but has become an important window for the early prevention and control of chronic diseases such as osteoporosis, cardiovascular disease, glucose and lipid metabolism disorders, and cognitive decline.