Researchers from the University of Osaka and collaborating institutions developed an autonomous solid-state nanopore that combines sensing, memory, and signal generation in a single device. Unlike conventional nanopores, the sensor continually reshapes itself through chemical reactions, producing unique electrical signatures as molecules pass through, providing a basis for memory. The device successfully identified a variety of nucleotides and amino acids, providing a new platform for molecular sensing and future iontronic computing.

Insilico Medicine (“Insilico”, HKEX:3696), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced the launch of the Drug Discovery and Development (DDD) Benchmarks as a Service (BaaS). It is a pioneering standardized evaluation framework anchored in carefully decontaminated real-world data and proprietary validated programs. for measuring how frontier AI and foundation models built on other architectures perform on real-world tasks across medicinal chemistry, chemical synthesis, disease biology, clinical development, and longevity research.

Researchers discover a new way of switching a material between two fundamentally different magnetic states using an electric current, paving the way for energy-efficient cryogenic devices

Quantum fluctuations influence direction-dependent electrical transport in chiral magnets, report researchers from Science Tokyo. In chiral magnetic systems, electric current flows differently depending on its direction, but the role of quantum effects in this behavior has remained unclear. Through theoretical analysis, the researchers showed that chiral magnetic systems exhibit logarithmic temperature dependence at low temperature, offering new insights into electron transport in magnetic materials. These findings are expected to play a crucial role in spintronics.

Hybrid quantum sources are essential for developing large-scale quantum networks. However, heterogeneous single-photon sources have different spectral and temporal networks, necessitating modifications and synchronizations that lead to losses and the need for additional resources. In a new study, researchers have successfully achieved indistinguishable photon generation between two physically dissimilar quantum sources: warm atomic ensembles and quantum dots. The two sources also demonstrated high visibility two-photonic interference, marking a key step for future quantum networks.

How much load can a crumpled sheet bear, and does size matter? A new study of two-dimensional macromolecules, a class of ultrathin sheet-like materials, shows that at equal packing density smaller sheets carry higher compressive loads than larger ones. Coarse-grained simulations and compression tests on paper, aluminum foil, PDMS, and silicone rubber reveal a universal “smaller is stronger” rule rooted in denser internal ridge networks, offering a new design principle for lightweight, high-strength structural metamaterials.

This review summarizes recent advances in wearable uric acid sensors, covering electrochemical and optical detection mechanisms, performance-enhancement strategies, device integration, and emerging applications. It highlights progress in sensitivity, selectivity, anti-fouling performance, self-calibration, and user comfort, while identifying persistent challenges in long-term stability, interference resistance, multimodal monitoring, clinical validation, data security, and commercialization. Future directions emphasize intelligent, sustainable, and personalized sensing platforms.

By sending quantum information through a storm, researchers at The University of the Witwatersrand in Johannesburg, South Africa, have shown that the information in light can be kept completely intact, even though the light itself was completely warped beyond recognition.