Indoles, which form the backbone of many bioactive compounds, are valuable in drug development but are difficult to modify at certain positions. Researchers at Chiba University have developed a cost-effective method using a copper-based catalyst to selectively attach alkyl groups to the C5 position, which has been especially challenging to target. This approach simplifies the synthesis of indole-based precursors and is expected to lead to the development of novel drug candidates in the future.  

Researchers at Beijing Institute of Technology have experimentally demonstrated anomalous topological pumping in hyperbolic lattices - a phenomenon impossible in conventional materials and Euclidean structures. Published in Science Bulletin, this work reveals how these curved-space structures can simulate high-dimensional quantum physics while exhibiting unique boundary-dependent transport.

A research team from the University of Basel, Switzerland, has developed a new molecule modeled on plant photosynthesis: under the influence of light, it stores two positive and two negative charges at the same time. The aim is to convert sunlight into carbon-neutral fuels.

A study led by Jun Cheng from Xiamen University and collaborators introduces a new workflow for recommending relay catalysis pathways. The workflow uses large language models (LLMs) to extract and organize catalytic reaction data, and combines this with a self-built catalysis knowledge graph (Cat-KG). The system automatically filters and recommends high-quality, traceable multi-step pathways, helping researchers design catalytic reactions more efficiently.

POSTECH and SNU Discover Breakthrough Material for Carbon-Free Hydrogen Production.

All-inorganic CsPbI₃ quantum dots (QDs) are regarded as promising candidates for advanced display materials due to their outstanding optoelectronic properties. However, conventional high-temperature thermal injection methods struggle with precise bandgap tuning, making it challenging to achieve pure red emission from CsPbI₃QDs. Now, in a study published in Science Bulletin, researchers from Zhejiang University of Technology have developed a thermally stable ethylammonium (EA⁺) doping strategy for CsPbI₃ QDs, achieving Rec.2020-standard pure-red perovskite light-emitting diodes (PeLEDs) with a high external quantum efficiency exceed 26%. The key innovation lies in an in situ acid–base equilibrium reaction that generates thermally stable ethylammonium oleate. This allows for the successful synthesis of EA⁺-doped CsPbI₃ QDs via high-temperature thermal injection, enabling precise emission tuning (630-650 nm) and exceptional spectral stability. The breakthrough opens new avenues for high-performance display technologies.