American College of Cardiology committed to heart disease prevention, treatment for all
Meeting Announcement
Updates every hour. Last Updated: 9-Sep-2025 14:11 ET (9-Sep-2025 18:11 GMT/UTC)
The American College of Cardiology is showing its commitment to health equity by hosting a Health Equity Summit for leaders across cardiology and a program for young scholars from the American Association of Indian Physicians’ National Native American Youth Initiative (NNAYI) to ensure the most vulnerable populations are receiving life-saving cardiovascular disease prevention education and treatments.
Many early-career scientists continue their academic careers at the same university where they studied, a practice known as academic inbreeding. A researcher at the HSE Institute of Education analysed the impact of academic inbreeding on publication activity in the natural sciences and mathematics. The study found that the impact is ambiguous and depends on various factors, including the university's geographical location, its financial resources, and the state of the regional academic employment market. A paper with the study findings has been published in Research Policy.
Endogenous AICAR (Acadesine) demonstrates significant therapeutic potential as a phase III clinical agent for the treatment of adverse cardiovascular reactions to coronary artery bypass grafting and as a phase I/II clinical agent for chronic lymphocytic leukemia. However, its biosynthetic mechanism remains poorly defined. Previous study demonstrated that AICAR was significantly enriched in the Fusarium solani mutant veAOE14, which overexpressed the global regulator VeA. In May 2025, the research team led by Professor Jichuan Kang from the Engineering and Research Center for Southwest Biopharmaceutical Resource of National Education Ministry of China, Guizhou University, published a research paper titled “MtfA, a C2H2 transcriptional regulator, negatively regulates PRPS2-mediated biosynthesis of the adenosine analogue Acadesine in Fusarium solani” in the journal Mycology.
This study elucidated, at the molecular level, the regulatory mechanism by which VeA overexpression enhances AICAR production in Fusarium solani. The team established a three-tier regulatory network model (VeA-MtfA-PRPS2) (Figure 1), laying an important foundation for the engineering of filamentous fungal strains for AICAR biosynthesis.
Tufts University has signed a memorandum of understanding with Indian Institute of Science to establish a framework for the development of a range of possible initiatives jointly pursued by the two institutions.
Abstract
Purpose – This study investigates the causal relationship and mechanisms between the development of digital finance and household carbon emissions. Its objective is to explore how digital finance can influence the carbon footprint at the household level, aiming to contribute to the broader understanding of financial innovations' environmental impacts.
Design/methodology/approach – The research combines macro and micro data, employing input-output analysis to utilize data from the China Household Finance Survey (CHFS) for the years 2013, 2015, 2017, and 2019, national input-output tables, and Energy Statistical Yearbooks. This approach calculated CO2 emissions at the household level, including the growth rate of household carbon emissions and per capita emissions. It further integrates the Peking University Digital Financial Inclusion Index of China (PKU-DFIIC) for 2012–2018 and corresponding urban economic data, resulting in panel data for 7,191 households across 151 cities over four years. A fixed effects model was employed to examine the impact of digital finance development on household carbon emissions.
Findings – The findings reveal that digital finance significantly lowers household carbon emissions. Further investigation shows that digital transformation, consumption structure upgrades, and improved household financial literacy enhance the restraining effect of digital finance on carbon emissions. Heterogeneity analysis indicates that this mitigating effect is more pronounced in households during the nurturing phase, those using convenient payment methods, small-scale, and urban households. Sub-index tests suggest that the broadening coverage and deepening usage of digital finance primarily drive its impact on reducing household carbon emissions.
Practical implications – The paper recommends that China should continue to strengthen the layout of digital infrastructure, leverage the advantages of digital finance, promote digital financial education, and facilitate household-level carbon emission management to support the achievement of China's dual carbon goals.
Originality/value – The originality of this paper lies in its detailed examination of the carbon reduction effects of digital finance at the micro (household) level. Unlike previous studies on carbon emissions that focused on absolute emissions, this research investigates the marginal impact of digital finance on relative increases in emissions. This method provides a robust assessment of the net effects of digital finance and offers a novel perspective for examining household carbon reduction measures. The study underscores the importance of considering heterogeneity when formulating targeted policies for households with different characteristics.