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Updates every hour. Last Updated: 20-Jun-2026 14:16 ET (20-Jun-2026 18:16 GMT/UTC)
Multifunctional deer antler decellularized hydrogel provides a new synergistic therapeutic strategy for diabetic wounds
Tsinghua University PressDiabetic wounds are complicated to heal due to factors such as infection, excessive inflammation, and impaired angiogenesis. Now, a groundbreaking, innovative hydrogel dressing has emerged, synthesized from the decellularized extracellular matrix of deer antler and a therapeutic metal-phenolic network. This multifunctional material opens up new prospects for chronic wound management by synergistically exerting antibacterial, antioxidant, and anti-inflammatory effects while promoting robust angiogenesis and tissue regeneration.
- Journal
- Nano Research
Potential of novel nanomedicine combining bioactivation and PROTAC technology for lung cancer treatment
Tsinghua University PressA research team has developed an innovative nanodrug platform, NPβ-lap+PRO, for precise non-small cell lung cancer treatment. This system combines NQO1 bioactivation therapy with PROTAC technology and overcome drug solubility and targeting limitations. The design features a PLGA nanoparticle core co-encapsulating β-lapachone and a PARP1-targeting PROTAC molecule, shielded by a pH-responsive gadolinium-tannic acid shell. The platform's paramagnetic properties enable MRI tracking of drug distribution. Experiments confirm effective tumor accumulation and pH-triggered drug release. In A549 models, the system induces PARP1 degradation, disrupts DNA repair, and amplifies β-lap-NQO1-reactive oxygen species production, resulting in enhanced DNA damage and apoptosis.
- Journal
- Nano Research
Unveiling hidden fungal allies: diversity and distribution of AMF in Nigerian vegetable farms
South China Botanical Garden, Chinese Academy of Sciences- Journal
- Biological Diversity
- Funder
- Tertiary Education Trust Fund
Zn2+-triggered mineralized hydrogel for enhanced deep burn wound healing
Tsinghua University PressA multifunctional hydrogel (HRZn) was fabricated through in situ mineralization and dynamic crosslinking of HA, Rhein, and Zn²⁺, resulting in enhanced mechanical properties and sustained release of bioactive components. In vivo evaluations demonstrated its potent efficacy in accelerating the healing of S. aureus-infected deep burn wounds.
- Journal
- Nano Research
Dual-polymer strategy engineers a high-performance catalyst for green urea synthesis
Tsinghua University PressA novel catalyst featuring a unique Ni−O−Si interface, engineered through a dual-polymer modification, enables efficient urea production from carbon dioxide and nitrate waste. This breakthrough offers a sustainable, energy-saving alternative to the traditional, energy-intensive industrial process, achieving high yield, selectivity, and long-term stability under ambient conditions.
- Journal
- Nano Research
A molecular bridge too far? No – polymer platforms now make precision immune activation a reality
China Anti-Cancer AssociationCancer immunotherapy has saved lives, but it often falls short due to off-target toxicity and weak tumor-specific immune responses.
- Journal
- Cancer Biology & Medicine
Metabolism-regulating microspheres: design principles, therapeutic applications across multisystem diseases, and future perspectives
ResearchIn January 2026, the team led by Huang Wei, Zhao Chen and Lei Yiting from the First Affiliated Hospital of Chongqing Medical University, in collaboration with the team of João F. Mano from the University of Aveiro, published a review article in Research entitled "Metabolism-Regulating Microspheres: Design Principles, Therapeutic Applications Across Multisystem Diseases, and Future Perspectives".
- Journal
- Research
- Funder
- National Natural Science Foundation of China, Natural Science Foundation of Chongqing, China, Chongqing Medical Youth Top-notch Talent Program, China Postdoctoral Science Foundation, General Project of Chongqing Natural Science Foundation, Major Project of Chongqing Municipal Education Commission, Hong Kong Scholars Program, Science and Technology Research Project of Chongqing Education Commission
More versus better: Artificial intelligence, incentives, and the emerging crisis in peer review
University of Oregon- Journal
- Organization Science
New lotus leaf biochar shows promise for cleaning toxic beryllium from mining wastewater
Biochar Editorial Office, Shenyang Agricultural University- Journal
- Biochar