A research team from the Beijing Institute of Technology (BIT) and Yinhe Hangtian has achieved a major advance in orbit mechanics by developing an analytical method capable of directly predicting spacecraft trajectories under third-body gravitational perturbations. This work, recently published in the Chinese Journal of Aeronautics, resolves a long-standing challenge in celestial dynamics and provides a new theoretical tool for deep-space exploration and autonomous spacecraft control.

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability. Disruption of these systems contributes to major liver diseases, including non-alcoholic fatty liver disease, alcoholic liver disease, drug-induced liver injury, viral hepatitis, and hepatocellular carcinoma, by impairing adenosine triphosphate synthesis, increasing oxidative stress, and altering metabolic pathways. Recent advances have clarified the structural-functional interdependence of individual complexes within SCs, revealing their dynamic remodeling in response to physiological stress and pathological injury. These insights open opportunities for clinical translation, such as targeting SC stability with pharmacological agents, nutritional strategies, or gene therapy, and employing mitochondrial transplantation in cases of severe mitochondrial failure. Precision medicine approaches, incorporating multi-omics profiling and patient-derived models, may enable individualized interventions and early detection using SC integrity as a biomarker. By linking molecular mechanisms to therapeutic strategies, this review underscores the potential of mitochondrial-targeted interventions to improve outcomes in patients with liver disease.

Environmental conditions on the seabed around fish farms generally improve the farther north you go in Norway.

One million births in Norway over 17 years have a story to tell: Maternity wards with greater numbers of births have safer births. 

New Review Integrates Human, Animal, and Cellular Evidence to Reframe AD as a Triad-Centered Disorder

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by memory loss, cognitive impairment, and widespread neuronal dysfunction. Although amyloid and tau pathologies have dominated the field for decades, growing evidence suggests that AD arises from broader homeostatic failures rather than a single molecular trigger.

Asthma is a chronic inflammatory airway disease affecting over 300 million people worldwide, and viral infections remain among the strongest triggers of acute exacerbations. Enterovirus D68 (EV-D68), in particular, has been repeatedly linked to severe asthma attacks in children, yet the host mechanisms that determine susceptibility remain poorly defined.

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT. This method enables precise assessment of the tumor microenvironment characteristics of pancreatic cancer and individualized guidance for chemotherapy regimens. It covers scenarios such as prognostic stratification of resectable pancreatic cancer, efficacy prediction of AG chemotherapy regimens for unresectable pancreatic cancer, and cross-cohort validation of multimodal imaging. The paper, titled "Noninvasive Computed Tomography-Based Quantification of Tumor Fibrosis Predicts Pancreatic Cancer Response to Gemcitabine/Nab-Paclitaxel", was published in Research (Research, 2025, 0937, DOI: 10.34133/research.0937).