Article Highlights
Updates every hour. Last Updated: 2-Nov-2026 22:17 ET (3-Nov-2026 03:17 GMT/UTC)
Small change, big impact: Intraoperative prostate compression in HIFU focal therapy
Higher Education PressA review published in UroPrecision synthesizes clinical evidence on high-intensity focused ultrasound for localized prostate cancer and highlights that intraoperative prostate compression is a promising technical refinement that enhances treatment precision and outcomes.
- Journal
- UroPrecision
Prostatic STUMP: Benign or malignant? The answer isn’t always clear
Higher Education PressA review published in UroPrecision synthesizes current knowledge on prostatic stromal tumor of uncertain malignant potential (STUMP), a rare prostatic neoplasm with unpredictable clinical behavior. The review, based on 84 patients from 14 studies, highlights the demographic, clinical, and pathological characteristics, diagnostic approaches, and treatment modalities for STUMP.
- Journal
- UroPrecision
A systems-level study revisits high glucose uptake in cancer cells through the lens of intracellular pH homeostasis
Higher Education PressHigh glucose uptake by cancer cells is one of the most widely recognized features of tumor metabolism and provides an important biological basis for positron emission tomography/computed tomography (PET/CT) imaging. Although this phenotype is commonly attributed to the energetic and biosynthetic demands of rapid proliferation, glucose-derived carbon is also distributed among multiple downstream pathways.
- Journal
- Quantitative Biology
Multi-omics map reveals how pear seeds awaken
Maximum Academic PressA research team has uncovered a multilayered regulatory network that controls pear seed germination by integrating metabolomic, transcriptomic, and microRNA analyses.
- Journal
- Seed Biology
Fine-tuning lipid nutrition for largemouth bass larvae
Maximum Academic PressA research team has identified an optimal lipid range for granulated microdiets in largemouth bass larvae, showing that dietary fat can strongly shape growth, feed efficiency, nutrient retention, liver condition, and intestinal development.
- Journal
- Animal Advances
A chain entanglement-stabilized injectable zwitterionic polymer hydrogel: Towards long-term vitreous substitute application
Science China PressMany vitreoretinal disorders, including retinal detachment (rhegmatogenous, exudative, or tractional), macular holes, proliferative vitreoretinopathy, diabetic retinopathy, and vitreous hemorrhage, often require vitrectomy with retinal repair, followed by intraocular tamponade to stabilize the retina and preserve ocular integrity. The tamponade agents most used in clinical practice are expansile gases and silicone oil. Although these materials can effectively support postoperative retinal reattachment, they remain limited in terms of long-term stability and biosafety. Complications such as cataract formation, elevated intraocular pressure, intraocular inflammation, and retinal injury associated with silicone oil emulsification may still occur. To address this challenge, Prof. Jianhai Yang and Prof. Wenguang Liu (Tianjin University), together with Prof. Xiaorong Li and Prof. Xiaoli Xing (Tianjin Medical University Eye Hospital) developed an injectable zwitterionic polymer hydrogel based on poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC).
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- National Science Review
High-resolution simulations reveal regional climate evolution over China since the Last Glacial Maximum and shed light on the Holocene temperature conundrum
Science China PressSince the Last Glacial Maximum, the Earth’s climate system has undergone pronounced temperature and hydroclimatic changes. This long-term evolution provides an important context for understanding the natural background of modern climate change and the response of the climate system to external forcing. Over China, climate evolution exhibits substantial regional heterogeneity under the combined influence of the East Asian monsoon and the complex topography of the Tibetan Plateau. Using high-resolution dynamical downscaling simulations, Professor Liang Ning and colleagues at Nanjing Normal University systematically investigated millennial-scale climate evolution over China since the Last Glacial Maximum. The results show that the regional climate model provides a more detailed representation of the spatial heterogeneity of temperature and precipitation associated with complex terrain. In addition, the contrasting Holocene trends of summer cooling and winter warming over northern China, the Tibetan Plateau, and northwestern China provide a new seasonal perspective on the Holocene temperature conundrum between proxy reconstructions and climate-model simulations. The study was published in the 2026 Issue 8 of the Chinese and English editions of SCIENCE CHINA Earth Sciences.
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- Science China Earth Sciences
Hybrid AI agent merges fire forecasting and LLMs for building emergency response
Higher Education PressPublished in Engineering, this research from PolyU and Guangzhou Institute of Industrial Technology develops a ConvLSTM-Fire deep learning model to repair broken sensor data and reconstruct 2D building temperature fields. Paired with a ChatGPT-4o-based LLM self-driven agent, the hybrid system converts real-time fire thermal data into actionable emergency guidance. Quantitative tests prove full 2D temperature inputs greatly improve the accuracy of LLM firefighting decisions, supporting voice-aided on-site response for occupants and firefighters.
- Journal
- Engineering
LLM-built knowledge graphs refine student cognitive diagnosis, study finds
Higher Education PressPublished in Engineering, this study introduces HCGCDM, an LLM-powered cognitive diagnosis model built on heterogeneous concept graphs. Unlike traditional tools that only capture prerequisite knowledge links, it automatically mines three types of concept relations via RAG. Tailored graph encoders and adaptive weighting boost student proficiency assessment accuracy, with ablation and LLM comparison experiments verifying its effectiveness and the impact of LLM capability on diagnostic performance.
- Journal
- Engineering