This study aims to develop a medical “dry laboratory” model that treats healthcare data as the primary research subject and employs computational science and AI as core methodologies. Based on the practice of a large tertiary hospital, we present a construction framework featuring a full-cycle model spanning data cultivation, governance, value extraction, and ecological feedback—transforming medical data from a static resource into a living asset. Innovatively, the “dry laboratory” was integrated into the residency training rotation to systematically cultivate data literacy. Practice has shown that the framework establishes the “dry laboratory” as a digital research entity, creating a closed-loop system that integrates clinical practice with data analytics, significantly enhancing the usability of multimodal data and enabling scalable training in data competence. In conclusion, the medical “dry laboratory” represents a new digital research paradigm distinct from traditional wet laboratories. Its implementation provides a reference framework and introduces an integrated “dry-wet” research model combining wet-lab experiments with data cultivation, demonstrating significant value for enhancing medical innovation, cultivating interdisciplinary talent, and advancing smart healthcare.

This paper clarified the antecedents, attributes, consequences, and empirical referents of safe care that may contribute to safer care and help healthcare professionals ensure patient safety.

Ahead of World Mental Health Day on October 10, attention is turning to the question of what causes psychological strain at work. A study by Bielefeld University shows that inappropriate tasks are not the only factor associated with exhaustion. Changes in day-to-day work can also leave employees feeling exhausted, even when the number of burdensome tasks decreases. Perceived uncertainty plays an important role.

Microplastics and nanoplastics are increasingly detected in the environment and human biological samples, raising concerns about their potential health effects. A new review published in Med Research highlights particle size as a key factor determining how these plastic particles interact with biological barriers and organs. Nanoplastics can more readily enter cells and subcellular structures, where they are associated with mitochondrial dysfunction, oxidative stress, ferroptosis, and inflammatory signaling. Larger microplastics, in contrast, primarily cause mechanical barrier disruption and persistent immune activation. The review compares these size-dependent effects across the intestine, liver, kidney, lung, and brain and discusses emerging intervention strategies and major gaps in translating experimental findings to human health.