Fungi are increasingly resistant to antifungals, and the variation in resistance has significantly increased. This is evident from the analysis of more than 12,000 lung samples collected over thirty years in Dutch hospitals. In addition, a resistant infection in a patient almost always consists of different fungal strains, making treatment more challenging. This study by Radboud university medical center and public health institute RIVM has been published in The Lancet Microbe.

Junk food firms have more than 90 current sponsorship deals within top UK sports amid growing concerns over their impact on public health, finds an investigation published by The BMJ today.

https://www.sciencedirect.com/journal/acta-pharmaceutica-sinica-b/vol/15/issue/6

Acta Pharmaceutica Sinica B (APSB) was founded with the goal of creating a global high-level forum centred around drug discovery and pharmaceutical research/application. APSB was included by Chemical Abstracts in 2011, accepted by PubMed Central in 2015, indexed by Science Citation Index in 2017 and has evolved to become one of the most important international journals in the field of pharmaceutical sciences.

https://doi.org/10.1016/j.apsb.2025.04.007

This new article publication from Acta Pharmaceutica Sinica B, discusses how a photodynamic nanohybrid system reverses hypoxia and augments anti-primary and metastatic tumor efficacy of immunotherapy.

https://doi.org/10.1016/j.apsb.2025.04.018

This new article publication from Acta Pharmaceutica Sinica B, discusses how ALKBH3-regulated m¹A of ALDOA potentiates glycolysis and doxorubicin resistance of triple negative breast cancer cells.

https://doi.org/10.1016/j.apsb.2025.04.008

This new article publication from Acta Pharmaceutica Sinica B, discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.

https://doi.org/10.1016/j.apsb.2025.04.001

This new article publication from Acta Pharmaceutica Sinica B, discusses how a psychological stress-activated NR3C1/NUPR1 axis promotes ovarian tumor metastasis.