MicroRNA-27a has been shown to stimulate both the wingless-type integration site family, or Wnt signaling, and the bone morphogenetic protein pathways to actively promote bone regeneration, according to a recent study from Institute of Science Tokyo, Japan. Their important findings shed light on the intrinsic cellular pathways and mechanisms that are critical for the development of new bone-like tissue and could inform the design and development of future tissue regeneration therapies.

The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated vaccinia virus strain originally developed for smallpox, is a promising option for countering the mpox virus. Exploring this potential further, researchers employed a cross-species immunological analysis to provide new insights into LC16m8’s immunogenicity and safety against mpox. The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated vaccinia virus strain originally developed for smallpox, is a promising option for countering the mpox virus. Exploring this potential further, researchers employed a cross-species immunological analysis to provide new insights into LC16m8’s immunogenicity and safety against mpox.

Researchers at Umeå University, Sweden, and Michigan State University, USA, have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health. The discovery opens the door for further research towards developing new antibiotics against chlamydia.

The efforts of a research team from Bochum and Würzburg give hope for new treatment approaches for dangerous tropical diseases. The researchers have compiled a high-precision inventory of the membrane proteins of cell organelles of the African sleeping sickness pathogen. “Some of these proteins contain components that are specific to parasites and differ significantly from those of the host cells,” explains Professor Ralf Erdmann from Ruhr University Bochum, Germany. As a result, they are a good target for potential active substances. The researchers report their findings in the journal Cell Reports from May 27, 2025.