Combined screening and online cognitive-behavior skills-building program reduces burnout, anxiety, depression and suicidal thoughts in nurses
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Updates every hour. Last Updated: 31-Oct-2026 10:16 ET (31-Oct-2026 14:16 GMT/UTC)
Researchers have developed biodegradable particles with microscopic needles that painlessly puncture the skin to help it absorb drugs delivered through patches or creams. The work is described in Advanced Healthcare Materials.
A research team comprising Associate Professor FUNAKOSHI Yohei, Associate Professor YAKUSHIJIN Kimikazu, Professor MINAMI Hironobu, and Associate Professor OHJI Goh of Kobe University, together with graduate student MASUDA Genki, then-graduate student IIZUMI Shunsuke, Associate Professor OHUE Masahito, and colleagues at the Institute of Science Tokyo, has developed a new analysis method, LM-QASAS. This method combines antibody language models with B-cell receptor (BCR) repertoires(*1) collected before and after vaccination to identify and track candidate BCR sequences that are likely to have responded to an immune stimulus, without using a database of known antigen-specific antibodies. LM-QASAS extends QASAS(*2; Quantification of Antigen-Specific Antibody Sequence), a method for quantitatively evaluating immune responses to a specific antigen through antigen-receptor repertoire analysis
A team led by the University of Osaka researchers discovered that cells producing IgG1 antibodies multiply more, are less prone to cell death in the spleen, and migrate more efficiently to the bone marrow, where long-lived antibody-producing cells can become established. Understanding how these cells gain these advantages could help researchers design vaccines that provide longer-lasting protection against infection.
Researchers in Denmark have found that girls whose mothers took paracetamol during pregnancy had smaller ovaries, fewer ovarian follicles (the structures that contain immature eggs), smaller uteruses and lower levels of reproductive hormones at three months old. In a study published on Wednesday in Human Reproduction Open, the researchers said their results were consistent with findings from several previous studies in animals. However, they noted that, as this was an observational study, the findings do not establish a direct cause-and-effect relationship.
Taking fewer daily steps at a faster pace or more steps at a slower pace may substantially lower the risk of early death by up to 43 per cent, new research from Monash University and the University of Sydney has found.
Published today in the British Journal of Sports Medicine, the research also found that walking at a brisker pace may be the sweet spot for those with sedentary lifestyles.